Results 81 to 90 of about 41,400 (238)

Single-cell deconvolution of 3,000 post-mortem brain samples for eQTL and GWAS dissection in mental disorders [PDF]

, 2021
Yongjin Park, Liang He, José Dávila-Velderrain, Lei Hou, Shahin Mohammadi, Hansruedi Mathys, Zhuyu Peng, David A. Bennett, Li‐Huei Tsai, Manolis Kellis   +9 more
openalex   +1 more source

OrchidMD: An Integrated and User‐Interactive Orchid Multi‐Omics Database for Mining Genes and Biological Research

Plant Biotechnology Journal, EarlyView.
ABSTRACT The Orchidaceae family, with its unparalleled species diversity among angiosperms, is integral to ornamental, medicinal, cultural, and ecological value. Multi‐omics techniques have proven invaluable for the identification of candidate genes and the advancement of functional genomics research. Nevertheless, the application of these technologies
Yonglu Wei, Zengyu Lin, Qi Xie, Jie Gao, Jianpeng Jin, Jie Li, Chuqiao Lu, Guangying Ye, Wenkang Li, Chuanfeng Huang, Dengqi Yang, Qi Liu, Genfa Zhu, Fengxi Yang   +13 more
wiley   +1 more source

eQTL epistasis – challenges and computational approaches

Frontiers in Genetics, 2013
The determination of eQTL epistasis - a form of functional interaction between genetic loci that affect gene expression - is an important step towards the thorough understanding of gene regulation.
Yang eHuang, Stefan eWuchty, Teresa M Przytycka   +2 more
doaj   +1 more source

(Re)-conciliation of genetics and genomics approaches for cotton fiber quality improvement [PDF]

, 2008
The integration of genomics and plant breeding is driven by the increasing availability of sequence resources and by technological developments. The simultaneous measurement of the expression of thousands of genes is possible, and comparisons between ...
Al-Ghazi, Yves, Arioli, Tony, Claverie, Michel, Dennis, Elizabeth, Derycker, Ruud, Forestier-Chiron, Nelly, Giband, Marc, Jacobs, John, Jean, Janine, Lacape, Jean-Marc, Llewellyn, Danny, Viot, Christopher   +11 more
core  

Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors. [PDF]

, 2015
Genome-wide association studies have identified over 70 single-nucleotide polymorphisms (SNPs) associated with breast cancer. A subset of these SNPs are associated with quantitative expression of nearby genes, but the functional effects of the majority ...
Brenner, Steven E, Camarda, Roman, Caswell, Jennifer L, Goga, Andrei, Hu, Donglei, Huntsman, Scott, Zaitlen, Noah, Zhou, Alicia Y, Ziv, Elad   +8 more
core   +2 more sources

Genome‐Wide Association Study Elucidates the Genetic Architecture of Manganese Tolerance in Brassica napus

Plant, Cell &Environment, EarlyView.
ABSTRACT Brassica napus (canola) is a significant contributor to the world's oil production and is cultivated across continents, yet acidic soils with aluminium (Al3+) and manganese (Mn2+) toxicities limit its production. The genetic determinants underlying natural variation for acidic soil tolerance in canola are unknown and need to be determined ...
Harsh Raman, Zetao Bai, Brett McVittie, Sourav Mukherjee, Hugh D. Goold, Yuanyuan Zhang, Nay Chi Khin, Yu Qiu, Nawar Shamaya, Shengyi Liu, Regine Delourme, Barry J. Pogson, Sureshkumar Balasubramanian, Rosy Raman   +13 more
wiley   +1 more source

Genetic control of longissimus dorsi muscle gene expression variation and joint analysis with phenotypic quantitative trait loci in pigs

BMC Genomics, 2019
Background Economically important growth and meat quality traits in pigs are controlled by cascading molecular events occurring during development and continuing throughout the conversion of muscle to meat.
Deborah Velez-Irizarry, Sebastian Casiro, Kaitlyn R. Daza, Ronald O. Bates, Nancy E. Raney, Juan P. Steibel, Catherine W. Ernst   +6 more
doaj   +1 more source

Integrating eQTL and GWAS data characterises established and identifies novel migraine risk loci [PDF]

, 2023
Ammarah Ghaffar, Dale R. Nyholt
openalex   +1 more source

When Metabolomics Meets Quantitative Genetics: An Integrative Strategy to Elucidate Plant Resistance Mechanisms

Plant, Cell &Environment, EarlyView.
ABSTRACT Gene pyramiding in crop varieties offers a promising strategy to achieve sustainable production and reduce reliance on pesticides. However, stacking resistance genes without understanding their biological functions may result in transient protection.
Romane Lapous, Komla Exonam Amegan, Bernard Caromel, Charles‐Eric Durel, Anne‐Violette Lavoir, Julie Ferreira de Carvalho, Romain Larbat   +6 more
wiley   +1 more source

Segregation of regulatory polymorphisms with effects on the gluteus medius transcriptome in a purebred pig population.

PLoS ONE, 2012
BackgroundThe main goal of the present study was to analyse the genetic architecture of mRNA expression in muscle, a tissue with an outmost economic importance for pig breeders.
Angela Cánovas, Ramona N Pena, David Gallardo, Oscar Ramírez, Marcel Amills, Raquel Quintanilla   +5 more
doaj   +1 more source