Results 31 to 40 of about 695,106 (268)
Guideline for standardized approach in the treatment of the Mal de Debarquement syndrome
Frontiers in NeurologyIntroductionMal de Debarquement Syndrome (MdDS) is a debilitating neuro-otological disorder. Patients experience almost continuously a perception of self-motion.
Catho Schoenmaekers +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Wearable, stable, highly sensitive hydrogel–graphene strain sensors
Beilstein Journal of Nanotechnology, 2019 A stable and highly sensitive graphene/hydrogel strain sensor is designed by introducing glycerol as a co-solvent in the formation of a hydrogel substrate and then casting a graphene solution onto the hydrogel in a simple, two-step method.
Jian Lv +8 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Topology made visible through standing waves in a spinning fluid
Communications PhysicsWave-topology interactions underlie phenomena across physics, from condensed matter to cosmology, with the Aharonov-Bohm (AB) effect providing a paradigmatic example.
Aditya Singh +5 more
doaj +1 more source
Effectively Incorporating Small Reserves into National Systems of Protected and Conserved Areas
DiversityReceived wisdom has argued that large protected areas are superior to small reserves, based on island biogeography theory, economies of scale, and the need to sustain viable populations of top predators and other large ranging or dispersive species.
Nigel Dudley +3 more
doaj +1 more source
Multi-photon resonances in Josephson junction-cavity circuits
New Journal of Physics, 2021 We explore the dissipative dynamics of nonlinearly driven oscillator systems tuned to resonances where multiple excitations are generated. Such systems are readily realised in circuit QED systems combining Josephson junctions with a microwave cavity and ...
Ben Lang, Andrew D Armour
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Prolonged microgravity induces reversible and persistent changes on human cerebral connectivity
Communications Biology, 2023 rs-fMRI is used to investigate human brain connectivity changes induced by prolonged microgravity in cosmonauts before and after spaceflight, with both persistent and reversible location specific changes in connectivity being observed.
Steven Jillings +20 more
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Geosciences, 2023 Discontinuum Bonded Block Modeling (BBM) represents a potential tool for support design, as these models can reproduce both the rock fracturing process and the influence of reinforcement on unsupported ground. Despite their strengths, discontinuum models
Sankhaneel Sinha, Gabriel Walton
doaj +1 more source