Results 41 to 50 of about 3,155,500 (300)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Topology made visible through standing waves in a spinning fluid
Communications PhysicsWave-topology interactions underlie phenomena across physics, from condensed matter to cosmology, with the Aharonov-Bohm (AB) effect providing a paradigmatic example.
Aditya Singh +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Particle Yields and Ratios within Equilibrium and Non-Equilibrium Statistics
, 2019 In characterizing the yields and ratios various of well identified particles in the ALICE experiment, we utilize extensive {\it additive} thermal approaches, to which various missing states of the hadron resonances are taken into consideration, as well ...
Elyazeed, Eman R. Abo +2 more
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Infinite sequential Nash equilibrium [PDF]
, 2013 In game theory, the concept of Nash equilibrium reflects the collective stability of some individual strategies chosen by selfish agents. The concept pertains to different classes of games, e.g. the sequential games, where the agents play in turn.
Roux, Stephane Le
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Geosciences, 2023 Discontinuum Bonded Block Modeling (BBM) represents a potential tool for support design, as these models can reproduce both the rock fracturing process and the influence of reinforcement on unsupported ground. Despite their strengths, discontinuum models
Sankhaneel Sinha, Gabriel Walton
doaj +1 more source
Tolling, Capacity Selection and Equilibrium Problems with Equilibrium Constraints [PDF]
, 2008 An Equilibrium problem with an equilibrium constraint is a mathematical construct that can be applied to private competition in highway networks. In this paper we consider the problem of finding a Nash Equilibrium regarding competition in toll pricing on
Koh, Andrew, Shepherd, Simon
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Correlated equilibria, good and bad : an experimental study [PDF]
, 2008 We report results from an experiment that explores the empirical validity of correlated equilibrium, an important generalization of the Nash equilibrium concept. Specifically, we seek to understand the conditions under which subjects playing the game of
Duffy, John, Feltovich, Nick
core +3 more sources