Results 51 to 60 of about 3,155,500 (300)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Dynamics of many-body quantum synchronisation
We analyse the properties of the synchronisation transition in a many-body system consisting of quantum van der Pol oscillators with all-to-all coupling using a self-consistent mean-field method.
C Davis-Tilley, C K Teoh, A D Armour
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
pre-equilibrium (prior equilibrium) [PDF]
Citation: 'pre-equilibrium (prior equilibrium)' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.P04810 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
openaire +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Essential planetary health workers: Positioning rangers within global policy
Our planet is facing increasing challenges: climate change, biodiversity loss, pandemics, poverty, and many other problems closely linked to a deteriorating environment.
Sue Stolton +14 more
doaj +1 more source
Hyperchaos in a Bose-Hubbard Chain with Rydberg-Dressed Interactions
We study the chaos and hyperchaos of Rydberg-dressed Bose–Einstein condensates (BECs) in a one-dimensional optical lattice. Due to the long-range, soft-core interaction between the dressed atoms, the dynamics of the BECs are described by the extended ...
Gary McCormack, Rejish Nath, Weibin Li
doaj +1 more source
Equilibrium unemployment [PDF]
A search-theoretic general equilibrium model of frictional unemployment is shown to be consistent with some of the key regularities of unemployment over the business cycle. In the model the return to a job moves stochastically. Agents can choose either to quit and search for a better job, or continue working. Search generates job offers that agents can
Gomes, Joao F +2 more
openaire +5 more sources
Relations between Heat Exchange and R\'{e}nyi Divergences
In this work, we establish an exact relation which connects the heat exchange between two systems initialized in their thermodynamic equilibrium states at different temperatures and the R\'{e}nyi divergences between the initial thermodynamic equilibrium ...
Wei, Bo-Bo
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

