Results 61 to 70 of about 1,270,442 (315)
Evidence for Biodiversity Conservation in Protected Landscapes
Land, 2016 A growing number of protected areas are defined by the International Union for Conservation of Nature (IUCN) as protected landscapes and seascapes, or category V protected areas, one of six protected area categories based on management approach. Category
Nigel Dudley +4 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Solid-Liquid Equilibrium Study of Binary System Saturated Fatty Acid in Short Chain Alcohols
Unsaturated fatty acids are potential to be used for preventing degenerative diseases and developing brain function in babies. Separation of unsaturated fatty acids from saturated fatty acids efficiently achieved by urea complexation fractionation method.
Plawi, Rudang Suryoadhi Suryatmoko +2 more
core +1 more source
Essential planetary health workers: Positioning rangers within global policy
Conservation Letters, 2023 Our planet is facing increasing challenges: climate change, biodiversity loss, pandemics, poverty, and many other problems closely linked to a deteriorating environment.
Sue Stolton +14 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
New Journal of Physics, 2016 We study the out-of-equilibrium dynamics of dissipative gases of atoms excited to two or more high-lying Rydberg states. This situation bears interesting similarities to classical binary (in general p -ary) mixtures of particles.
Ricardo Gutiérrez +2 more
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
New Journal of Physics, 2023 Coherent quantum transduction between microwave and optical signals is of great importance for long-distance quantum communication. Here we propose a novel scheme for the implementation of nonreciprocal single-photon state conversion between microwave ...
Jikun Xie +5 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source