Results 71 to 80 of about 3,132,300 (299)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Non-equilibrium fluctuations and metastability arising from non-additive interactions in dissipative multi-component Rydberg gases

open access: yesNew Journal of Physics, 2016
We study the out-of-equilibrium dynamics of dissipative gases of atoms excited to two or more high-lying Rydberg states. This situation bears interesting similarities to classical binary (in general p -ary) mixtures of particles.
Ricardo Gutiérrez   +2 more
doaj   +1 more source

Study of the phase transition in the 3d Ising spin glass from out of equilibrium numerical simulations

open access: yes, 2006
Using the decay of the out equilibrium spin-spin correlation function we compute the equilibrium Edward-Anderson order parameter in the three dimensional binary Ising spin glass in the spin glass phase.
A Tarancón   +16 more
core   +3 more sources

Equilibrium Cycle: A “Dynamic” Equilibrium

open access: yes
In this paper, we introduce a novel equilibrium concept, called the equilibrium cycle, which seeks to capture the outcome of oscillatory game dynamics. Unlike the (pure) Nash equilibrium, which defines a fixed point of mutual best responses, an equilibrium cycle is a set-valued solution concept that can be demonstrated even in games where best ...
Walunj, Tushar Shankar   +3 more
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Nonreciprocal single-photon state conversion between microwave and optical modes in a hybrid magnonic system

open access: yesNew Journal of Physics, 2023
Coherent quantum transduction between microwave and optical signals is of great importance for long-distance quantum communication. Here we propose a novel scheme for the implementation of nonreciprocal single-photon state conversion between microwave ...
Jikun Xie   +5 more
doaj   +1 more source

Trade Equilibrium, Jobs, & Stimulus [PDF]

open access: yes, 2009
As long as the U.S. continues to have huge trade deficits, the American jobs would continue to be off-shored and no net new jobs can be created. Spending billions of American stimulus dollars would end up stimulating foreign economies.
Bhandari, Narendra C.
core   +1 more source

Equilibrium and non-equilibrium fluctuations in a glass-forming liquid

open access: yes, 2008
Glass-forming liquids display strong fluctuations -- dynamical heterogeneities -- near their glass transition. By numerically simulating a binary Weeks-Chandler-Andersen liquid and varying both temperature and timescale, we investigate the probability ...
Azita Parsaeian   +3 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

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