Results 61 to 70 of about 1,429,876 (274)

Stability of equilibrium states in the Zhukovski case of heavy gyrostat using algebraic methods

, 2011
We study the stability of the equilibrium points of a skew product system. We analyze the possibility to construct a Lyapunov function using a set of conserved quantities and solving an algebraic system.
Aeyels, Birtea, Birtea, Comănescu, Gavrilov, Guirao Juan, Marsden, Puta, Rouche, Vera, Vera, Wittenburg   +11 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A semantical approach to equilibria and rationality

, 2009
Game theoretic equilibria are mathematical expressions of rationality. Rational agents are used to model not only humans and their software representatives, but also organisms, populations, species and genes, interacting with each other and with the ...
A. Borodin, A.J. Power, A.K. Simpson, D. Pearce, D.B. Bernheim, E. Moggi, J. Nash, J. Power, J.M. Smith, J.M.E. Hyland, J.R. Norris, L. Samuelson, L.E. Dubins, M. Hasegawa, N. Benton, N. Nisan, P. Wadler, R.L. Crole, R.M. Axelrod, S. Abramsky, S. Abramsky, S.L. Bloom, É. Tardos   +22 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A Discrete Numerical Solution of The SIR Model with Horizontal and Vertical Transmission

Cauchy: Jurnal Matematika Murni dan Aplikasi, 2019
The aim of this paper is to is to generalize the SIR model with horizontal and vertical transmission. In this paper, we develop the discrete version of the model. We use Euler method to approximate numerical solution of the model.
Trija Fayeldi
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Study of mathematical models of type 2 diabetes mellitus and its complications

Jurnal Natural
The rapid increase in type 2 diabetes mellitus (DM) cases in Indonesia, driven by hereditary factors and unhealthy lifestyles, poses significant health challenges.
AFIATUN MAGHFIRAH, BASRI A. GANI, MARWAN RAMLI, MUHAMMAD IKHWAN   +3 more
doaj   +1 more source

ON COMPUTATIONAL DIFFERENCES OF CRITICAL POINTS ON EQUILIBRIUM CURVE

International Journal for Computational Civil and Structural Engineering, 2017
In this paper, we discuss the features of investigating the type of the critical point on the equilibrium curve (bifurcation point or limit point). There are new ideas about the completion of the initial equilibrium at the limit point or bifurcation ...
Gaik A. Manuylov, Sergey B. Kosytsyn, Maxim M. Begichev   +2 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source