Results 61 to 70 of about 26,786 (257)
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Solution parallelization of softening plasticity problems
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2011 Parallelization of deformation-damage coupling boundary value problem solution is considered. In definition the equations of the strength we used the principle of equivalence of deformations in a real and relatively undamaged structures.
I. E. Adeyanov, Ya. M. Klebanov
doaj +3 more sources
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
On Comparison, Equivalence and Addition of Magnitudes
Principia: An International Journal of Epistemology, 2019 A theory of magnitudes involves criteria for their comparison, equivalence and addition. We examine these aspects from an abstract viewpoint, stressing independence and definability.
Paulo A. Veloso +2 more
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Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
The principle of no equivalence: an agent-based model
Cognitive LinguisticsSynonymy avoidance has been a recent topic of theoretical contention in Construction Grammar. This paper defines, unpacks, and models the ‘principle of no equivalence’ previously sketched by Leclercq, Benoît & Cameron Morin. 2023.
Leclercq Benoît +2 more
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Simulating Indefinite Causal Order With Rindler Observers
Frontiers in Physics, 2020 Realization of indefinite causal order (ICO), a theoretical possibility that even causal relations between physical events can be subjected to quantum superposition, apart from its general significance for the fundamental physics research, would also ...
Aleksandra Dimić +6 more
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FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Is equivalence principle valid for quantum gravitational field?
Results in PhysicsEntanglement can be generated through the gravitational interaction between two massive bodies that are initially in a product state. This shows that the gravitational field is quantum.
Baocheng Zhang
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