Results 81 to 90 of about 163,262 (305)
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On linear equivalence and Phelps codes. Addendum
A new class of perfect 1-error correcting binary codes, so called RRH-codes, are identified, and it is shown that every such code is linearly equivalent to a perfect code obtainable by the Phelps construction.
Olof Heden, Martin Hessler
openaire +1 more source
Source code optimization using equivalent mutants [PDF]
A mutant is a program obtained by syntactically modifying a program's source code; an equivalent mutant is a mutant, which is functionally equivalent to the original program. Mutants are primarily used in \emph{mutation testing}, and when deriving a test suite, obtaining an equivalent mutant is considered to be highly negative, although these ...
Jorge López +2 more
openaire +2 more sources
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Spreading Code Design for a MC-CDMA Based GNSS Pilot Signal
MC-CDMA can represent an alternative to classical DS-CDMA for the design of GNSS ranging signals. A first requirement MC-CDMA signals must fulfill is that their generation on a satellite payload be feasible.
Meurer, Michael +7 more
core +1 more source
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Computer-based analysis of spatial frames according to second order theory
The analysis of spatial frames formed of beam elements according to the second order theory is presented in the paper. The stiffness matrix and equivalent load vector elements are derived from the exact solution of the corresponding differential ...
Ljiljana Žugić +2 more
doaj +1 more source
Orthogonality for Quantum Latin Isometry Squares [PDF]
Goyeneche et al recently proposed a notion of orthogonality for quantum Latin squares, and showed that orthogonal quantum Latin squares yield quantum codes.
Benjamin Musto, Jamie Vicary
doaj +1 more source
The Trellis Complexity of Equivalent Binary [17, 9] Quadratic Residue Codes is Five [PDF]
[[abstract]]It is known that equivalent linear block codes may have different minimal trellis structures. The minimum complexity among all minimal trellis structures of equivalent codes is defined as the trellis complexity of the class of equivalent ...
Chung-Chin Lu, Yan-Yih Wang
core

