Results 101 to 110 of about 4,452,390 (325)

Asymptotic symmetries and subleading soft photon theorem in effective field theories

Journal of High Energy Physics, 2018
In [1, 2] it was shown that the subleading soft photon theorem in tree level amplitudes in massless QED is equivalent to a new class of symmetries of the theory parameterized by a vector field on the celestial sphere.
Alok Laddha, Prahar Mitra
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

An equivalent statement of the Riemann Hypothesis using the Abel-Plana Formula

, 2023
This paper shows how the Abel-Plana expression for the Riemann zeta function can be transformed into an equation with a sum of complex logarithms of non-trivial zeta zeros. This equation, in case of 𝞯(s)=0, can only be valid for non-trivial zeta-zeros. An equivalent statement of the Riemann hypothesis has been formulated and an attempt of proof added.
openaire   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

A problem with nonlocal integral condition of the second kind for one-dimensional hyperbolic equation

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2016
In this paper, we consider a problem for a one-dimensional hyperbolic equation with nonlocal integral condition of the second kind. Uniqueness and existence of a generalized solution are proved. In order to prove this statement we suggest a new approach.
Ludmila S Pulkina, Alesya E Savenkova
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Fractional Aspects of the Erdős-Faber-Lovász Conjecture

Discussiones Mathematicae Graph Theory, 2015
The Erdős-Faber-Lovász conjecture is the statement that every graph that is the union of n cliques of size n intersecting pairwise in at most one vertex has chromatic number n.
Bosica John, Tardif Claude
doaj   +1 more source

The digital conception of sigma - delta D/A converter implemented into FPGA

Communications, 2000
D/A converters are technical means which allow mutual communication between discrete and analog systems. Then base function is accurately comprehended in the statement "D/A converters create bridge between digital and analog world".
Oldrich Kovar, Juraj Micek
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source