Results 41 to 50 of about 2,214,130 (267)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
On a more accurate reverse Mulholland-type inequality with parameters
Journal of Inequalities and Applications, 2019 By the use of the weight coefficients, the idea of introducing parameters and Hermite–Hadamard’s inequality, a more accurate reverse Mulholland-type inequality with parameters and the equivalent forms are given.
Leping He, Hongyan Liu, Bicheng Yang
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A version of Carleman’s formula summation of the Riemann ζ -function on the critical line [PDF]
Математичні Студії, 2011 A version of Carleman's formula for functions holomorphic in a rectangle is proved. It is applied to the evaluation of the integral of ζ -function logarithm with the summing factor exp(−t) along the critical line.
A. M. Brydun, P. A. Yatsulka
doaj
From Bolzano-Weierstra{\ss} to Arzel\`a-Ascoli
, 2012 We show how one can obtain solutions to the Arzel\`a-Ascoli theorem using suitable applications of the Bolzano-Weierstra{\ss} principle. With this, we can apply the results from \cite{aK} and obtain a classification of the strength of instances of the ...
Brattka +13 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
, 2002 Grothendieck's conjecture on p-curvatures predicts that an arithmetic differential equation has a full set of algebraic solutions if and only if its reduction in positive characteristic has a full set of rational solutions for almost all finite places ...
Di Vizio, Lucia
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
TECA, 2011 The paper shows some ways of publishing Italian journals from XVII century to early years of ‘800. It contains large set of exemples of important titles issued again as monographics in context without ties with journalism yet; some reprints are also ...
Rudj Gorian
doaj +1 more source