Results 71 to 80 of about 4,452,390 (325)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Boolean Algebra Application in Analysis of Flight Accidents [PDF]
INCAS Bulletin, 2015 Fault tree analysis is a deductive approach for resolving an undesired event into its causes, identifying the causes of a failure and providing a framework for a qualitative and quantitative evaluation of the top event.
Casandra Venera BALAN
doaj +1 more source
Interpolation and Extrapolation Statements equivalent to the Riemann Hypothesis
, 2023 The goal of this paper is twofold; on one hand we wish to present some statements that can be formulated in terms of Interpolation theory which are equivalent to the truth or the falseness of the Riemann Hypothesis, on the other hand we will use a key result of the Jawerth-Milman extrapolation to improve on a well-known criterion by Beurling and Nyman ...
openaire +2 more sources
Homotopy equivalences between p-subgroup categories [PDF]
, 2014 Let p be a prime number and G a finite group of order divisible by p. Quillen showed that the Brown poset of nonidentity p-subgroups of G is homotopy equivalent to its subposet of nonidentity elementary abelian subgroups.
Jesper, M. Møller, Matthew Gelvin
core
An Equivalent Statement to Nicolas' Criterion
, 2015 Nicolas' criterion for the Riemann Hypothesis (RH) is an inequality based on primorials and the Euler totient function. The aim of this paper is to reformulate Nicolas' criterion and prove the equivalent statement. I will show that the reformulation is bounded and montonic using Chebyshev's function and results on prime numbers.
openaire +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
A Hilbert-type integral inequality in the whole plane related to the kernel of exponent function
Journal of Inequalities and Applications, 2018 By using real analysis and weight functions, we obtain a few equivalent statements of a Hilbert-type integral inequality in the whole plane related to the kernel of exponent function with intermediate variables.
Yanru Zhong, Meifa Huang, Bicheng Yang
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Reporting of Noninferiority and Equivalence Randomized Trials [PDF]
JAMA, 2006 The CONSORT (Consolidated Standards of Reporting Trials) Statement, including a checklist and a flow diagram, was developed to help authors improve their reporting of randomized controlled trials. Its primary focus was on individually randomized trials with 2 parallel groups that assess the possible superiority of one treatment compared with another ...
Piaggio, Gilda +5 more
openaire +3 more sources