Results 161 to 170 of about 63,057 (294)

Radiative Thermal Management for Extreme Environments: Mechanisms and Design Strategies

Advanced Materials, EarlyView.
In this review, we discuss the fundamental mechanisms of radiative cooling and solar heating, material and structural design strategies, hybrid approaches integrating additional heat transfer pathways, and durability‐oriented designs addressing environmental stresses.
Hyung Rae Kim, Haeseong Kim, Joo Hwan Ko, Gil Ju Lee, Dae‐Hyeong Kim, Young Min Song   +5 more
wiley   +1 more source

METTL14-mediated m6A modification enhances USP22-ERα axis to drive breast cancer malignancy

Pharmacological Research
The abundance and activity of estrogen receptor alpha (ERα) are tightly regulated by ubiquitin-specific peptidase 22 (USP22) during the progression of breast cancer (BCa).
Xuefen Zhuang, Shusha Yin, Ji Cheng, Wenshuang Sun, Zesen Fang, Yujie Xiang, E.-ying Peng, Yu Yao, Yuting Li, Xiaoyue He, Li Lu, Yuanfei Deng, Hongbiao Huang, Gengxi Cai, Yuning Liao   +14 more
doaj   +1 more source

ERα Responses in Different Cellular States of Breast Cancer

, 2019
ERα is a central transcription factor, activated by ligand-dependent (estradiol [E2]) or –independent pathways (e.g. cAMP). ERα is expressed in two thirds of all breast tumors (ERα-positive). The final stage of breast cancer is metastasis.
Apostolopoulou, Aikaterini
core   +1 more source

PKA-Mediated stabilization of FoxH1 negatively regulates ERα activity

, 2019
Estrogen receptor α (ERα) mediates the mitogenic effects of estrogen. ERα signaling regulates the normal growth and differentiation of mammary tissue, but uncontrolled ERα activation increases the risk to breast cancer.
여창열
core   +1 more source

Recent Advances in Plasma‐Enhanced Atomic Layer Etching for Next‐Generation Nanofabrication

Advanced Materials Interfaces, EarlyView.
Continued semiconductor miniaturization demands atomic‐scale patterning and ultralow surface roughness beyond the capabilities of conventional reactive ion etching. This review highlights advances in isotropic and anisotropic plasma‐enhanced atomic layer etching since 2020, covering fundamental mechanisms, applications across major semiconductor ...
Shih‐Nan Hsiao
wiley   +1 more source

Unlocking Terahertz Steganography: Authentication of Hidden Images in Flexible Media

Advanced Materials Technologies, EarlyView.
Hidden information in multilayered devices, such as steganographic portraits, is detected and authenticated using reflection‐mode terahertz time‐domain imaging. Image reconstruction relies on a dedicated figure‐of‐merit obtained by integrating the signal intensity over the time‐window associated with the reflection from the metallic mirror backing the ...
Tiziana Ritacco, Francesca Vittorioso, Dimitrios C. Zografopoulos, Romeo Beccherelli, Walter Fuscaldo   +4 more
wiley   +1 more source

Learning‐Based Soft Robotic Grasping: Recent Progress and Remaining Challenges

Advanced Robotics Research, EarlyView.
This review analyzes learning‐based soft robotic grasping from a pipeline‐oriented perspective, encompassing soft gripper design, multimodal sensing, and learning‐based planning and control. It surveys key neural network architectures and benchmark datasets and identifies critical challenges such as sim‐to‐real transfer, generalization, and continual ...
Arnab Majumder, Jelizaveta Konstantinova, Graham Deacon, Kaspar Althoefer   +3 more
wiley   +1 more source

High Oestrogen receptor alpha expression correlates with adverse prognosis and promotes metastasis in colorectal cancer

Cell Communication and Signaling
In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while oestrogen receptor beta (ERβ) is considered the dominant subtype.
Geriolda Topi, Shakti Ranjan Satapathy, Souvik Ghatak, Karin Hellman, Fredrik Ek, Roger Olsson, Roy Ehrnström, Marie-Louise Lydrup, Anita Sjölander   +8 more
doaj   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

ARL3 Enhances ERα Stability via USP10 Deubiquitination to Promote Endocrine Resistance and Drive Mitochondrial Metabolic Reprogramming in HR+ Breast Cancer

Advanced Science
The molecular mechanisms of estrogen receptor α (ERα)‐positive breast carcinogenesis and endocrine resistance remain unclear. This study identifies ADP‐ribosylation factor‐like protein 3 (ARL3) as a key oncogenic regulator overexpressed in ERα‐positive ...
Han Li, Yang Liu, Zehao Cai, Kang Li, Shun Gao, Ailin Lan, Dan Shu, Kuan He, Xin Liu, Yang Peng, Shipeng Guo, Haochen Yu, Aishun Jin, Meiying Shen, Shengchun Liu   +14 more
doaj   +1 more source