Results 161 to 170 of about 17,002 (210)

Tissue-specific transcriptomic responses and skeletal-muscle ultrastructural observations in Semah mahseer (<i>Tor douronensis</i>) under acute thermal and hypoxic conditions. [PDF]

Food Chem (Oxf)
Uchuwittayakul A, Phuthong W, Kong C, Rajitdumrong C, Adisornprasert Y, Kumwan B, Meachasompop P, Ely SSP, Vangnai K, Srikulnath K, Srisapoome P.   +10 more
europepmc   +1 more source

Competition between Der1 and ERAD-M substrates controls Hrd1 complex function. [PDF]

Proc Natl Acad Sci U S A
Russ JE, Peterson BG, Taylor S, Baldridge RD.   +3 more
europepmc   +1 more source

Endoplasmic reticulum stress in Hashimoto's thyroiditis: a candidate amplification node linking thyroid-specific vulnerability and immune dysregulation. [PDF]

Front Immunol
Si X, Guo Z, Jiao G, Zhang X, Ge Y, Qian J, Li X, Geng W, Yao S, Ding Z, Wu Y.   +10 more
europepmc   +1 more source

Enhancing Yeast Surface Display: UPR, ERAD, and ER Dynamics in Recombinant Protein Production. [PDF]

Food Technol Biotechnol
Martinić Cezar T, Paić A, Žunar B, Stuparević I, Mrša V, Teparić R.   +5 more
europepmc   +1 more source

Unfolded protein response in bronchopulmonary dysplasia: mechanisms, pathways, and therapeutic implications. [PDF]

Front Cell Dev Biol
Yu H, Guo Y, Wang X, Guo W, Zhang Y.
europepmc   +1 more source

Viruses Hijack ERAD to Regulate Their Replication and Propagation

International Journal of Molecular Sciences, 2022
Endoplasmic reticulum-associated degradation (ERAD) is highly conserved in yeast. Recent studies have shown that ERAD is also ubiquitous and highly conserved in eukaryotic cells, where it plays an essential role in maintaining endoplasmic reticulum (ER ...
Sen Zeng, Linke Zou, Feifan Zhao
exaly   +2 more sources

EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired

International Journal of Molecular Sciences, 2020
Endoplasmic reticulum (ER)-associated degradation (ERAD) is the main mechanism of targeting ER proteins for degradation to maintain homeostasis, and perturbations of ERAD lead to pathological conditions. ER-degradation enhancing α-mannosidase-like (
Cristian V A Munteanu, Ștefana M Petrescu, Gabriela N Chiritoiu   +2 more
exaly   +2 more sources

The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins [PDF]

Molecular Cell, 2018
Endoplasmic reticulum (ER)-associated degradation (ERAD) removes misfolded proteins from the ER membrane and lumen by the ubiquitin-proteasome pathway. Retrotranslocation of ubiquitinated substrates to the cytosol is a universal feature of ERAD that
Trey Ideker, Philipp A Jaeger, Chris Benner   +2 more
exaly   +2 more sources

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Smallpox eradication

Proceedings of the Royal Society of London. Series B. Biological Sciences, 1977
Abstract An intensified global programme to eradicate smallpox within 10 years was initiated by the World Health Organization in January 1967. This goal will virtually be achieved. Whereas an estimated 10-15 million cases had occurred in 44 countries in 1967, only one small focus and two known active cases still remained in December ...
openaire   +2 more sources