Results 101 to 110 of about 2,212 (246)
Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism
, 2018 N6-methyladenosine (m6A) is a chemical modification present in multiple RNA species, being most abundant in mRNAs. Studies on enzymes or factors that catalyze, recognize, and remove m6A have revealed its comprehensive roles in almost every aspect of mRNA
Yun-Gui Yang +3 more
core +1 more source
Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review
Advanced Science, EarlyView.Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh +8 more
wiley +1 more source
Proceedings of the National Academy of SciencesGene expression in the brain is typically evaluated using invasive biopsy or postmortem histology. Serum markers provide an alternative way to monitor the brain, but relatively few such markers exist. Additionally, the origin of serum markers often cannot be localized to a specific cell population, and monitoring dynamic changes in their gene ...
Shirin Nouraein +7 more
openaire +5 more sources
Biochemistry and Biophysics ReportsEukaryotic messenger RNAs (mRNAs) transcend their predominant function of protein encoding by incorporating auxiliary components that ultimately contribute to their processing, transportation, translation, and decay.
Mahbub Hasan +4 more
doaj +1 more source
Advanced Science, EarlyView.Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su +13 more
wiley +1 more source
Frontiers in ImmunologyN6-methyladenosine (m6A) methylation is the most common intramolecular modification in eukaryotic mRNA; its dynamic regulation depends on “writers” (methyltransferases: METTL3/METTL14/WTAP/VIRMA), “erasers” (demethylases: FTO/ALKBH5), and “readers ...
Jin Yang +8 more
doaj +1 more source
, 2017 A. Writer-coding genes are more abundant than eraser-coding genes. B. Writer proteins are significantly less abundant than all proteins (Ac p = 3.7*10−3, Ubq p = 1.4*10−5; Mann-Whitney test). C.
Ilan Smoly (3704866) +4 more
core +1 more source
Advanced Science, EarlyView.Two‐dimensional CuInP2S6 nanosheets are incorporated into a P(VDF‐TrFE) matrix to induce polarization‐cooperative ferroelectric coupling. The resulting P(VDF‐TrFE)/CuInP2S6 hybrid film exhibits reinforced ferroelectric ordering and reduced coercive electric fields compared with pristine P(VDF‐TrFE).
Yeonsu Jeong +10 more
wiley +1 more source
Advanced Science, EarlyView.Here, we present an optoelectronic synaptic memtransistor (OSMT) integrating photoresponsive IGZO with contact‐engineered HfO2, enabling electrically and optically tunable synaptic weights. The device demonstrates broad range of tunable conductance states and array‐level image processing, highlighting its potential for intelligent machine vision ...
Donghyun Kang +6 more
wiley +1 more source
Targeted Protein Degradation by Chimeric Small Molecules, PROTACs and SNIPERs
Frontiers in Chemistry, 2019 Technologies that induce targeted protein degradation by small molecules have been developed recently. Chimeric small molecules such as Proteolysis Targeting Chimeras (PROTACs) and Specific and Non-genetic IAP-dependent Protein Erasers (SNIPERs), and E3 ...
Mikihiko Naito +3 more
doaj +1 more source