Results 61 to 70 of about 13,813 (161)

Principal mechanisms of extracellular matrix‐mediated cell–cell communication in physiological and tumor microenvironments

The FEBS Journal, Volume 293, Issue 1, Page 26-41, January 2026.
Intracellular communication controls the processing of generated signals so that every cell type can successfully respond. The extracellular matrix (ECM) is a fundamental regulator of cell communication and signaling through the strict orchestration and functions of its bioactive components.
Zoi Piperigkou, Sylvia Mangani, Nikolaos E. Koletsis, Christos Koutsakis, Nicholas S. Mastronikolis, Marco Franchi, Nikos K. Karamanos   +6 more
wiley   +1 more source

The epidermal growth factor receptor/Erb-B/HER family in normal and malignant breast biology

, 2011
The EGFR/Erb-B receptor tyrosine kinases each play distinct and complementary roles in normal breast development. The four receptors form both homodimers and heterodimers in response to binding by ligands which show selectivity for one or more of the ...
Suzanne A. Eccles, Eccles, SA
core   +1 more source

Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4)

, 2012
Proteinase-activated receptors 4 (PAR(4)) is a class A G protein-coupled receptor (GPCR) recognized through the ability of serine proteases such as thrombin and trypsin to mediate receptor activation. Due to the irreversible nature of activation, a fresh
Robben, Joris, Cooke, Alexandra, Gould, Gwyn W., McIntosh, Kathryn A., Gould, Gwyn, Milligan, Graeme, Cunningham, Margaret Rose, Pediani, John D., Cooke, Alexandra E., McIntosh, Kathryn, Nilsson, Mary, Mundell, Stuart, Plevin, Robin, Cunningham, Margaret R., McIntosh, Kathryn A, Pediani, John D, Gould, Gwyn W, Pediani, John, Nilsson, Mary Francis, Cunningham, Margaret R, Cooke, Alexandra E   +20 more
core   +1 more source

Identification of serine 867 as new phosphorylation site on the GABA(B) receptor : characterization of physiological effects [PDF]

, 2011
The GABAB receptor is the metabotropic receptor for γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the mammalian central nervous system (CNS). The functional receptor is a heteromer consisting of a GABAB1 and GABAB2 subunit.
Abdel Aziz, Said
core   +1 more source

Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding.

, 2010
The transmembrane protein ephrin-B2 regulates angiogenesis, i.e. the formation of new blood vessels through endothelial sprouting, proliferation and remodeling processes.
Astin, J.W, Adams, RH, Nobes, CD, Astin, Jonathan, Adams, R.H, Bochenek, M.L, Nobes, C.D, Bochenek, ML, Dickinson, S   +8 more
core   +1 more source

Ephrin-B2 controls PDGFRβ internalization and signaling. [PDF]

, 2013
B-class ephrins, ligands for EphB receptor tyrosine kinases, are critical regulators of growth and patterning processes in many organs and species.
Höing, S, Turner, Christopher, Adams, RH, Nakayama, M, Nakayama, A, Lepore, JJ   +5 more
core   +1 more source

Papel do receptor ativado por proteinases-2 (par-2) no comportamento de coçar em camundongos [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pos-Graduação em Farmacologia, Florianópolis, 2009.O objetivo do presente estudo foi investigar os possíveis mecanismos e mediadores envolvidos no
Costa, Robson da
core  

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

The role of neural crest cells in the development, organisation and migration of the thymus

, 2010
Neural Crest (NC) derived mesenchyme has previously been shown to play an important role in the early development of the foetal thymus. Using Wnt1-Cre and Sox10-Cre mice crossed to Rosa26eYfp reporter mice, NC derived mesenchymal cells were revealed in
Foster, K.E.
core  

Abstract 2194: Novel receptor tyrosine kinases in osteosarcoma identified by phosphoproteomic and functional genomic screening

, 2010
Osteosarcoma is the most common primary bone malignancy and is largely attributed to rapidly growing bones of adolescents. Approximately one-third of patients succumb to pulmonary metastasis despite high-dose neoadjuvant chemotherapy protocols.
Edward M. Greenfield, Patrick J. Getty, Ashley N. Rettew   +2 more
core   +1 more source