Results 141 to 150 of about 58,467 (222)
This article presents identification and mapping of an epitope in the protein ErbB-2 which binds to the monoclonal antibody 4B8 intended for use in immunochemistry to estimate the level of ErbB-2 production.
M. B. Borgoyakova, A. A. Ilichev
doaj
p53、bcl-2和c-erbB-2在恶性卵巢上皮性肿瘤中的表达及临床意义
目的检测62例恶性卵巢上皮性肿瘤中p53、bcl-2和c-erbB-2的表达情况以探讨三种基因对恶性卵巢上皮性肿瘤的早期诊断及预后判断的意义。方法采用免疫组织化学方法检测p53b、cl-2 and c-erbB-2在恶性卵巢上皮性肿瘤中的表达及其与组织学分类,临床分期,腹水,淋巴结转移预后的关系。结果恶性卵巢上皮性肿瘤在p53、bcl-2 and c-erbB-2的表达阳性率分别52.23%,62.90%和45.16%与卵巢瘤组和正常组之间比较差异有显著性 ...
许天敏, 崔满华, 林杨, 何凯
doaj
Prognostic and clinical implications of c-erbB-2 expression in patients with oral cancer: A meta-analysis. [PDF]
Meng Y, Yang P, Ma L.
europepmc +1 more source
目的 探讨幽门螺杆菌感染与胃癌P53 、C erbB - 2的关系。方法 应用Warthin -Starry染色法检测幽门螺杆菌 ,免疫酶组化SP法检测P53 、C -erbB - 2基因蛋白。结果 Hp感染率在胃癌和癌前病变组中均高于对照组 ,而前两组差异无显著性 ,Hp感染与C erbB 2过度表达有关。P53 仅在胃癌组织中表达 ,Hp感染者与P53 过度表达有关 (P
房学东, 杨作森, 冯涛
doaj
Câncer de boca : expressão imuno-histoquímica de c-erbB-2, Bcl-2 e EGFR : estudo comparativo com leucoplasia e hiperplasia inflamatória [PDF]
5 p.Anormalidades em genes que regulam a proliferação e morte celular podem provocar inúmeras doenças entre elas o carcinoma epidermóide de boca. Tem sido relatado que alterações genéticas nas células tumorais predizem a agressividade biológica dos ...
Barros, Rosana Mara Giordano de +2 more
core
The Role of Human Epidermal Growth Factor Receptor 2 (HER2/neu) in Mucoepidermoid Carcinomas [PDF]
Shirin Saravani
doaj +1 more source
胃癌p53、c-erbB-2、p21、nm23基因表达的分布特点及其临床意义
目的为探讨手术切除胃癌组织p53、c-erbB-2、p21、nm23联合基因产物表达检测对胃癌诊断治疗及预后判断的价值。方法应用免疫组化技术检测了手术切除胃癌组织p53c、-erbB-2、p21、nm23基因产物表达。结果p53蛋白表达阳性率为36.4%46.7%,c-erbB-2为33.3%56.8%,p21为35.1%56.7%,nm23为30.0%70.5%。在非胃癌组织中(胃,十二指肠溃疡,胃息肉,重度不典型增生)未见c-erbB-2、p21、nm23基因表达。p53c、-erbB-2 ...
陈永胜 +4 more
doaj
ErbB-2 signaling in advanced prostate cancer progression and potential therapy [PDF]
Miller DR, Ingersoll MA, Lin MF.
europepmc +1 more source

