Results 1 to 10 of about 43,468 (143)
Effect of silencing C-erbB-2 on esophageal carcinoma cell biological behaviors by inhibiting IGF-1 pathway activation [PDF]
Journal of Cardiothoracic Surgery, 2021 Objective C-erbB-2 has been confirmed to be an oncogene that participates in cell growth, differentiation and division of tumors. We are wondered if its silenced expression can exert an anti-tumor effect. Therefore, this study is conducted to investigate
Zhigao Niu +4 more
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Ultrasound microbubble-mediated CRISPR/Cas9 knockout of in HEC-1A cells [PDF]
Journal of International Medical Research, 2019 Objective Epidermal growth factor receptor 2 (C-erbB-2) is one of the most frequently mutated oncogenes in human tumors. We aimed to evaluate the knockout efficiency of clustered regularly interspaced short palindromic repeat (CRISPR) technology using ...
Junhong Cai +3 more
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Evaluation of bcl-2, bax and c-erbB-2 Levels in Chronic Otitis Patients with or without Cholesteatoma [PDF]
Turkish Archives of Otorhinolaryngology, 2015 Objective:The aim of this study was to evaluate bcl-2, bax, and c-erbB-2 expressions in primary and secondary acquired cholesteatoma and to indicate the role of apoptosis and accompanying increased cellular proliferation in the pathogenesis of ...
Özgür Işık +7 more
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C-erbB-2 in Serum of Patients Receiving Fractionated Paclitaxel Chemotherapy
The International Journal of Biological Markers, 1999 Humanized anti-c-erbB-2 antibodies (Herceptin®) in a weekly schedule are a new therapeutic option for the treatment of c-erbB-2-positive, advanced breast cancer (ABC).
D. Lüftner, S. Schnabel, K. Possinger
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C-erbB-2 Oncoprotein in Gastric Carcinoma: Correlation with Clinical Stage and Prognosis
The International Journal of Biological Markers, 2001 The aim of this study was to investigate the expression of the oncogene c-erbB-2 in gastric tumors. Immunohistochemical study of the expression of c-erbB-2 was performed in formalin-fixed, paraffin-embedded sections from 82 gastric adenocarcinomas using ...
C.T.F. Oshima +3 more
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C-erbB-2 Expression in Primary Breast Cancer
The International Journal of Biological Markers, 1999 c-erbB-2 is an oncoprotein which is overexpressed in up to 40% of primary breast cancers. c-erbB-2 overexpression is a bad prognostic factor in patients with lymph node-positive disease.
E. Tagliabue +3 more
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Diagnostic Pathology, 2010 Background Endometrial carcinoma (EC) is the most common malignancy of the female genital tract. Gene alterations and overexpression of various oncogenes are important in tumor development.
Kandemir Nilufer +6 more
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The International Journal of Biological Markers, 1993 Selected murine monoclonal antibodies (MAb) have been shown to inhibit relevant tumor growth in vitro and in animal models. Recently, bispecific antibodies (BsMAb) have been developed which target cytolytic effector cells via one antibody binding site ...
I. Garcia De Palazzo +2 more
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JAI (Jurnal Anestesiologi Indonesia), 2009 Latar Belakang: Nyeri akut paska bedah memicu timbulnya gejala klinis patofisiologis, menekan respon imun, sehingga menyebabkan penurunan sistem imun yang akan menghambat penyembuhan luka. Levobupivakain, anestetik lokal durasi panjang efektif mengurangi
Curniawati Trisasi, Marwoto Marwoto
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Alterations of c-Myc and c-erbB-2 genes in ovarian tumours [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2009 Introduction. According to clinical and epidemiological studies, ovarian cancer ranks fifth in cancer deaths among women. The causes of ovarian cancer remain largely unknown but various factors may increase the risk of developing it, such as age, family ...
Pastor Tibor +8 more
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