Results 11 to 20 of about 43,518 (188)
C-erbB-2 in Serum of Patients with Breast Cancer
The International Journal of Biological Markers, 1999 c-erbB-2 is an oncoprotein which is overexpressed in some breast cancers. Recently it has been established that the extracellular domain of c-erbB-2 is shed into the serum of patients with breast cancer.
L. Harris +3 more
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Expression of MIF and c-erbB-2 in endometrial cancer. [PDF]
Mol Med Rep, 2016 The aim of the present study was to investigate the expression of c-erbB-2 and macrophage migration inhibitory factor (MIF) in endometrial cancer and to elucidate the significance of the early diagnosis and prognosis of endometrial cancer. The gene copy number of c‑erbB‑2 and MIF was characterized by reverse transcription quantitative polymerase chain ...
Xiao W +6 more
europepmc +4 more sources
c-Myb Repression of c- erbB-2 Transcription by Direct Binding to the c- erbB-2 Promoter [PDF]
Journal of Biological Chemistry, 1995 The c-myb proto-oncogene product (c-Myb) is a transcriptional activator that can bind to the specific DNA sequences. Although c-Myb also represses an artificial promoter containing the Myb binding sites, natural target genes transcriptionally repressed by c-Myb have not been identified.
G, Mizuguchi +7 more
openaire +2 more sources
Cytoplasmic staining of c-erbB-2 is not associated with the presence of detectable c-erbB-2 mRNA in breast cancer specimens [PDF]
International Journal of Cancer, 1998 The cell-surface receptor tyrosine kinase protein c-erbB-2 is immunocytochemically detected as membrane staining on the surface of cancer cells in 20-30% of cases of breast cancer, and its presence has been associated with poor prognosis for the patient. However, there have been numerous reports of immunocytochemical staining for c-erbB-2 solely in the
S L, Taylor +4 more
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Changes in c‐erbB‐2 Immunoexpression in Feline Endometrial Adenocarcinomas [PDF]
Reproduction in Domestic Animals, 2015 ContentsHuman epidermal growth factor receptor type 2 (c‐erbB‐2), an oncoprotein with potential prognostic marker and therapeutic use, is overexpressed in several human and animal tumours. But information regarding this molecule in feline tumours is scarce.
Saraiva, Ana Laura da Silva Santos +5 more
openaire +3 more sources
Folia Histochemica et Cytobiologica, 2010 The c-erbB-2 (HER-2/neu), EGF and EGFR (erbB-1) proteins, members of the epidermal growth factor receptor family, play a role in cell growth by binding to cell membrane receptors.
Katarzyna Guzinska-Ustymowicz +2 more
doaj +1 more source
Folia Histochemica et Cytobiologica, 2010 The family of epidermal growth factor (EGF, EGFR, c-erbB-2) plays a pivotal role in gastric cancer progression, invasion and metastasizing. Helicobacter pylori infection is known to contribute significantly to the formation and progression of gastric ...
Andrzej Kemona +3 more
doaj +1 more source
C-erbB-2 immunostaining: problems with interpretation. [PDF]
Journal of Clinical Pathology, 1994 AIMS--To assess the consistency and reproducibility of assessment of c-erbB-2 immunostaining, and to examine some of the problems relating to inter- and intraobserver variability in the documentation of positive staining; to profile the spectrum of cytoplasmic and membranous staining in a wide range of tumour types.
E W, Kay +4 more
openaire +2 more sources
Analytical Cellular Pathology, 1998 Amplification and overexpression of the c-erbB-2 oncogene are of prognostic significance in human breast cancer. Overexpression of c-erbB-2 is the result of gene amplification.
Melek Öztürk +4 more
doaj +1 more source
Preliminary study of p53 and c-erbB-2 expression in gallbladder cancer in Indian patients
BMC Cancer, 2006 Background The inactivation of the tumour suppressor gene and activation of the proto-oncogene are the key steps in the development of the human cancer. The p53 and c-erbB-2 are the best examples of it.
Singh Usha +4 more
doaj +1 more source