Results 41 to 50 of about 49,818 (236)

EGF and TGF-β1 effects on thyroid function [PDF]

open access: yes, 2011
Normal epithelial thyroid cells in culture are inhibited by TGF-β1. Instead, transformed thyroid cell lines are frequently resistant to its growth inhibitory effect. Loss of TGF-β responsiveness could be due to a reduced expression of TGF-β receptors, as
Gabriella Mincione   +7 more
core   +2 more sources

c-erbB-2 and p53 expression in fallopian tube carcinoma [PDF]

open access: yesCancer, 1995
Carcinoma of the fallopian tube is a rare gynecologic malignancy. Its histologic appearance and patterns of spread are similar to those of epithelial ovarian cancer. Alterations in the gene products of c-erbB-2 (HER-2/neu) and p53 are found commonly in ovarian tumors and may have prognostic relevance.
M Q, Lacy   +6 more
openaire   +2 more sources

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li   +7 more
wiley   +1 more source

Maspin and c-erbB-2 expression in correlation with microvessel density in invasive ductal breast cancer

open access: yesFolia Histochemica et Cytobiologica, 2011
Maspin is a unique member of the serpin family involved in regulation of cell migration, apoptosis and angiogenesis in breast and prostate cancers. In this study maspin expression in comparison with c-erbB-2 (HER2/neu) oncogene expression and microvessel
Izabela Berdowska   +2 more
doaj   +1 more source

C-erbB-2 as a Biomarker for Premalignant Potential of Oral Lichen Ruber [PDF]

open access: yes, 2004
Ovim istraživanjem nastojao se procijeniti mogući premaligni potencijal lezija oralnoga lihen rubera (OLR-a) određivanjem intenziteta ekspresije tkivnog antigena c-erbB-2 u odnosu prema kliničkom obliku i kliničkom statusu lezija.
Ahmed Pirkić   +2 more
core   +1 more source

Single‐Cell Computational Frameworks for Quantifying BET Bromodomain Inhibitor Resistance and Screening Re‐Sensitizer Drugs in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu   +6 more
wiley   +1 more source

乳癌における癌遺伝子産物の免疫組織学的検討 : C-erbB-2 product を中心に [PDF]

open access: yes, 1990
近年, 乳癌において癌遺伝子と予後因子との関連が注目きれているが, 未だ統ーした見解はえられていない 。その手法も核酸レベルで癌遺伝子の増幅, mutation を検出する方法と癌遺伝子産物を検出する方法に大別きれている。我々は, 新鮮凍結切片を用いてc- erbB-2 product, epidermal growthfactor receptor( EGFR), c-myc protein, estrogen receptor( ER) の免疫組織学的検討を行い既に報告しているが, 加えてc ...
田内 克典   +2 more
core   +1 more source

Breast cancer or metastasis? An unusual case of metastatic malignant pleural mesothelioma to the breast [PDF]

open access: yes, 2015
Background: Metastases to the breast from extramammary malignancies are very rare, and ruling out the diagnosis of primary breast tumor is important in order to decide on clinical management and predict prognosis.
Derme, Martina   +5 more
core   +2 more sources

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

open access: yesAdvanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija   +22 more
wiley   +1 more source

c-erbB-2 Oncoprotein Content in Gastric Cancer and in Adjacent Mucosa

open access: yesThe International Journal of Biological Markers, 2000
The aim of this study was to evaluate, by means of an immunoenzymatic assay, the membranous and cytosolic c-erbB-2 oncoprotein contents in primary tumors and in adjacent mucosa from gastric cancer patients.
I. García   +6 more
doaj   +1 more source

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