Results 81 to 90 of about 34,611 (189)

Epidermal Growth Factor Receptor and c-erbB-2 Contents in Unresectable (UICC R1 or R2) Gastric Cancer

open access: yesThe International Journal of Biological Markers, 2003
Background Epidermal growth factor receptor (EGFR) and c-erbB-2 are membrane receptors expressed in a variety of solid human cancers and directly correlated with poor prognosis.
I. García   +5 more
doaj   +1 more source

Correlation of c-erbB-2, EGF and EGFR expression with postoperative survival of patients with advanced carcinoma of the stomach.

open access: yesFolia Histochemica et Cytobiologica, 2010
The c-erbB-2 (HER-2/neu), EGF and EGFR (erbB-1) proteins, members of the epidermal growth factor receptor family, play a role in cell growth by binding to cell membrane receptors.
Katarzyna Guzinska-Ustymowicz   +2 more
doaj   +1 more source

Interkingdom Endodontic Biofilm Supernatant Induces a Biphasic Inflammatory and Metabolic Transcriptional Response in Dental Pulp Stem Cells In Vitro

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Objectives To investigate how soluble byproducts derived from a four‐species endodontic biofilm model impact the viability, transcriptomic profile, and inflammatory response of human dental pulp stem cells (DPSCs). Methods A sterile‐filtered supernatant was extracted from an established interkingdom endodontic biofilm model comprising ...
Saeed S. Alqahtani   +7 more
wiley   +1 more source

Coronary Microvascular Dysfunction: Epidemiology, Pathophysiology, Diagnosis, and Treatment

open access: yesMedComm, Volume 7, Issue 8, August 2026.
This visual summary illustrates the key aspects of coronary microvascular dysfunction (CMD) in angina with nonobstructive coronary artery disease (NOCAD), including epidemiology, pathophysiology (microvascular remodeling and endothelial dysfunction), the protective NRG‐1/ErbB signaling pathway, diagnostic methods, and both Western and traditional ...
Zhao Ge   +8 more
wiley   +1 more source

Overall Survival With Pyrotinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in HER2‐Positive Metastatic Breast Cancer: A Single‐Center Pooled Analysis

open access: yesThoracic Cancer, Volume 17, Issue 15, August 2026.
In this single‐center pooled analysis of HER2‐positive metastatic breast cancer, pyrotinib plus capecitabine was associated with significantly longer overall survival than lapatinib plus capecitabine. This survival benefit remained significant in a sensitivity analysis restricted to the randomized Phase II and III trials and after multivariable ...
Jialin Lin   +12 more
wiley   +1 more source

Exceptional Response of HER2‐Positive Breast Cancer to Osimertinib: A Case Report

open access: yesThoracic Cancer, Volume 17, Issue 16, August 2026.
An 83‐year‐old woman with synchronous EGFR L858R‐mutated lung adenocarcinoma and HER2‐positive breast cancer received osimertinib monotherapy for lung cancer without breast‐directed therapy. The breast tumor showed durable radiological and metabolic regression, with a Grade 3 therapeutic effect and HER2 amplification confirmed at postmortem biopsy ...
Hirotoshi Yasui   +10 more
wiley   +1 more source

Co-Targeting ErbB Receptors and the PI3K/AKT Axis in Androgen-Independent Taxane-Sensitive and Taxane-Resistant Human Prostate Cancer Cells. [PDF]

open access: yesCancers (Basel), 2022
Adediran S   +9 more
europepmc   +1 more source

Expression Landscape and Circadian Regulation of lncRNAs in the Kidney

open access: yesActa Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Recent multi‐omics work shows that the diurnal rhythmicity of kidney function is associated with circadian oscillations in renal mRNA, protein and metabolite abundances. Yet circadian regulation of renal lncRNAs, which are emerging as important modulators of diverse (patho)physiological processes, remains largely unexplored. Here, we provide a
Leonore Wigger   +4 more
wiley   +1 more source

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