Results 81 to 90 of about 34,611 (189)
Background Epidermal growth factor receptor (EGFR) and c-erbB-2 are membrane receptors expressed in a variety of solid human cancers and directly correlated with poor prognosis.
I. García +5 more
doaj +1 more source
The c-erbB-2 (HER-2/neu), EGF and EGFR (erbB-1) proteins, members of the epidermal growth factor receptor family, play a role in cell growth by binding to cell membrane receptors.
Katarzyna Guzinska-Ustymowicz +2 more
doaj +1 more source
ABSTRACT Objectives To investigate how soluble byproducts derived from a four‐species endodontic biofilm model impact the viability, transcriptomic profile, and inflammatory response of human dental pulp stem cells (DPSCs). Methods A sterile‐filtered supernatant was extracted from an established interkingdom endodontic biofilm model comprising ...
Saeed S. Alqahtani +7 more
wiley +1 more source
ERBB Receptors and Their Ligands in the Developing Mammary Glands of Different Species: Fifteen Characters in Search of an Author. [PDF]
Morato A, Accornero P, Hovey RC.
europepmc +1 more source
Coronary Microvascular Dysfunction: Epidemiology, Pathophysiology, Diagnosis, and Treatment
This visual summary illustrates the key aspects of coronary microvascular dysfunction (CMD) in angina with nonobstructive coronary artery disease (NOCAD), including epidemiology, pathophysiology (microvascular remodeling and endothelial dysfunction), the protective NRG‐1/ErbB signaling pathway, diagnostic methods, and both Western and traditional ...
Zhao Ge +8 more
wiley +1 more source
Structural arrangement of the active back-to-back dimer in N-glycosylated ErbB receptors is regulated by heterodimerization. [PDF]
Mashayekh-Poul R +2 more
europepmc +1 more source
In this single‐center pooled analysis of HER2‐positive metastatic breast cancer, pyrotinib plus capecitabine was associated with significantly longer overall survival than lapatinib plus capecitabine. This survival benefit remained significant in a sensitivity analysis restricted to the randomized Phase II and III trials and after multivariable ...
Jialin Lin +12 more
wiley +1 more source
Exceptional Response of HER2‐Positive Breast Cancer to Osimertinib: A Case Report
An 83‐year‐old woman with synchronous EGFR L858R‐mutated lung adenocarcinoma and HER2‐positive breast cancer received osimertinib monotherapy for lung cancer without breast‐directed therapy. The breast tumor showed durable radiological and metabolic regression, with a Grade 3 therapeutic effect and HER2 amplification confirmed at postmortem biopsy ...
Hirotoshi Yasui +10 more
wiley +1 more source
Co-Targeting ErbB Receptors and the PI3K/AKT Axis in Androgen-Independent Taxane-Sensitive and Taxane-Resistant Human Prostate Cancer Cells. [PDF]
Adediran S +9 more
europepmc +1 more source
Expression Landscape and Circadian Regulation of lncRNAs in the Kidney
ABSTRACT Recent multi‐omics work shows that the diurnal rhythmicity of kidney function is associated with circadian oscillations in renal mRNA, protein and metabolite abundances. Yet circadian regulation of renal lncRNAs, which are emerging as important modulators of diverse (patho)physiological processes, remains largely unexplored. Here, we provide a
Leonore Wigger +4 more
wiley +1 more source

