Results 101 to 110 of about 22,662 (208)

Spectral analysis of gene expression profiles using gene networks

, 2006
Microarrays have become extremely useful for analysing genetic phenomena, but establishing a relation between microarray analysis results (typically a list of genes) and their biological significance is often difficult.
Barillot, Emmanuel, Dutreix, Marie, Rapaport, Franck, Vert, Jean-Philippe, Zinovyev, Andrei   +4 more
core   +1 more source

Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study [PDF]

, 2013
Peer reviewedPublisher ...
Gow, Neil A R, Lee, Keunsook, Munro, Carol A, Pietro, Rosemeire C L R, Preechasuth, Kanya, Santos, Emerson, Severi, Juliana A, Souza-Moreira, Tatiana M, Vilegas, Wagner   +8 more
core   +4 more sources

4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection. [PDF]

, 2017
BackgroundChagas disease, caused by the protozoan Trypanosoma cruzi, is the leading cause of heart failure in Latin America. The clinical treatment of Chagas disease is limited to two 60 year-old drugs, nifurtimox and benznidazole, that have variable ...
Calvet, Claudia Magalhaes, Choi, Jun Yong, de Mesquita, Liliane Batista, de Souza Pereira, Mirian Claudia, Hirata, Ken, Lostracco-Johnson, Sharon, McKerrow, James H, Meuser-Batista, Marcelo, Nogueira, Alanderson, Podust, Larissa M, Roush, William R, Silva, Tatiana Araujo, Siqueira-Neto, Jair Lage, Suzuki, Brian, Thomas, Diane   +14 more
core   +3 more sources

Phosphatidylserine polarization is required for proper Cdc42 localization and for development of cell polarity. [PDF]

, 2010
We used genetically-encoded fluorescent probes to visualize the distribution of phosphatidylserine (PS) in live S. cerevisiae. The majority of the PS was found to reside in the cytosolic leaflet of the plasma membrane.
Gregory Fairn, Sergio Grinstein
core   +1 more source

Molecular actions of hypocholesterolaemic compounds from edible mushrooms [PDF]

, 2018
Cholesterol levels are strictly regulated to maintain its homeostasis; therefore, if it is not absorbed with the diet, the cholesterol biosynthetic pathway is enhanced and vice versa.
Gil-Ramírez, Alicia, Morales, Diego, Soler-Rivas, Cristina   +2 more
core   +1 more source

Hexaconazole promotes deoxynivalenol synthesis by interfering with farnesyl pyrophosphate metabolism in Fusarium graminearum

Ecotoxicology and Environmental Safety
Deoxynivalenol (DON) is primarily produced by Fusarium graminearum (F. graminearum) and widely contaminates cereal feedstuffs, posing a serious threat to livestock and poultry health.
Ping Yang, Sifan Jia, Kangle Peng, Desheng Qi   +3 more
doaj   +1 more source

trans-Cinnamic and Chlorogenic Acids Affect the Secondary Metabolic Profiles and Ergosterol Biosynthesis by Fusarium culmorum and F. graminearum Sensu Stricto

Toxins, 2017
Plant-derived compounds limiting mycotoxin contamination are currently of major interest in food and feed production. However, their potential application requires an evaluation of their effects on fungal secondary metabolism and membrane effects.
Tomasz Kulik, Kinga Stuper-Szablewska, Katarzyna Bilska, Maciej Buśko, Anna Ostrowska-Kołodziejczak, Dariusz Załuski, Juliusz Perkowski   +6 more
doaj   +1 more source

Synergistic Antifungal Effects of Honokiol and Fluconazole Against Oral Candida: Implications for Managing Drug‐Resistant Infections

Clinical and Experimental Dental Research
Objectives Antifungal drug resistance poses a major challenge in treating oral Candida infections. This study aimed to evaluate the antifungal activity of Honokiol, alone and combined with Fluconazole, against oral Candida isolates, and to investigate ...
Maribasappa Karched, Mohammad Irshad, Jawad M. Behbehani   +2 more
doaj   +1 more source

Ergosterol biosynthesis in Saccharomyces Cerevisiae

, 1972
Imperial Users ...
Davies, Penelope Jane, Davies, Penelope Jane   +1 more
openaire   +1 more source

The control of calcium metabolism by parathyroid hormone, calcitonin and vitamin D [PDF]

Advances in analysis of chemistry and physiology of parathyroid hormone, calcitonin, and Vitamin D are described along with development of techniques in radioassay methods.
Potts, J. T., Jr.
core   +1 more source