Results 51 to 60 of about 28,167 (222)
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki +4 more
wiley +1 more source
Ergot, caused by the fungus Claviceps purpurea (Fr.) Tul., belongs to the main constraints in seed production of Kentucky bluegrass (Poa pratensis L.).
Bohumír Cagaš, Radek Macháč
doaj +1 more source
Endophyte Infected Tall Fescue: Plant Symbiosis to Animal Toxicosis
Endophyte-infected fescue is a major cool season forage used for livestock production in the United States and through other areas of the world. A unique aspect of this forage resource is the symbiotic relationship with an endophytic fungus (Epichloë ...
Taylor D. Ferguson +2 more
doaj +1 more source
Abstract Objective The primary objective of this study was to evaluate opioid and barbiturate utilization before and after the first prescription of the calcitonin gene–related peptide receptor antagonist rimegepant in individuals with migraine. Background Although not recommended in migraine treatment guidelines, opioids and barbiturates are often ...
Noah Rosen +6 more
wiley +1 more source
Ergot alkaloids are a group of mycotoxins occurring in products derived from various grasses (e.g., rye) and have been regulated in the EU recently.
Maximilian Kuner +5 more
doaj +1 more source
Integrating gepants into clinical practice for the acute treatment of migraine
Abstract Objective To assess the role of small‐molecule calcitonin gene–related peptide receptor antagonists (gepants) in the acute treatment of migraine, particularly in relation to triptan treatments. Background Triptans have established efficacy and are widely prescribed for the acute treatment of migraine.
Richard B. Lipton +4 more
wiley +1 more source
The influence of low temperatures on the incidence of sugary disease on sorghum [PDF]
The relationship between pre-flowering climatic conditions and sugary disease incidence was quantified in grain and forage sorghum genotypes at two sowing periods (mid November and mid December).
Amauri Bogo +3 more
doaj +1 more source
Hybrid Varieties for Organic Cereals? Prospects and acceptance of hybrid breeding for organic production [PDF]
Hybrid breeding utilizes the advantages characterizing F1 plants in a targeted manner: Vigour, uniformity, and a combination of all dominant traits of the parental lines.
Arncken, Christine, Dierauer, Hansueli
core
Ergot caused by Claviceps purpurea is a problem for food and feed security in rye due to the occurrence of toxic ergot alkaloids (EAs). For grain elevators and breeders, a quick, easy-to-handle, and cheap screening assay would have a high economic impact.
Anna Kodisch +16 more
doaj +1 more source
ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and vasoprotective effects. This review aims to provide a comprehensive overview of LEO's pharmacokinetics, pharmacological mechanisms ...
Zhouyue Gu
wiley +1 more source

