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The role of ERK signaling pathways in mitochondrial dysfunction
Mitochondrial dysfunction plays a central role in the progression of different diseases by disrupting cellular energy balance and promoting epithelial degeneration, inflammation, and apoptosis. While mitochondria are key regulators of cellular stress responses, the effects of mitochondrial impairment on signaling pathway activation remain incompletely ...Budeš, Ana-Marija +4 more
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IL-27 Mediates Pro-Inflammatory Effects via the ERK Signaling Pathway During Preterm Labor
Frontiers in Immunology, 2021Nanlin Yin, Yuxin Ran, Dongni Huang
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Osteoblasts Regulate the Expression of ADAMTS and MMPs in Chondrocytes through ERK Signaling Pathway
Zeitschrift Fur Orthopadie Und Unfallchirurgie, 2023Weishan Wang
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Mechanisms of Selective Regulation of the ERK and PI3K Signaling Pathways
Kinases and phosphatases orchestrate cellular signaling not only through their opposing catalytic activities but also via scaffolds and regulatory partners that spatially and temporally organize them into precise signaling assemblies. The phosphoinositide 3-kinase (PI3K) and extracellular signal-regulated kinase (ERK) pathways are central regulators ofopenaire +1 more source