Results 51 to 60 of about 186,091 (248)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Psychological fatigue includes mental fatigue and burnout. In order to investigate the impact of psychological fatigue on athletes' response monitoring, event-related potentials technique is typically used, and the most critical indicator is error ...
Jin Li, Yanni Wang, Sihua Li
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Efficient measurement error mitigation with subsystem-balanced Pauli twirling
Measurement error mitigation (MEM) is essential for realizing reliable quantum computation. Model-free measurement error mitigation (MF-MEM) is an important class of MEM methods that employs Pauli twirling—typically with a random twirling set—to convert ...
Xiao-Yue Xu, Chen Ding, Wan-Su Bao
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
k-dimensional error-free deconvolution using the fermat number transform
AbstractThe paper presents the generalization of the one-dimensional deconvolution algorithm using the Fermat number transform for the k-dimensional deconvolution. The problems of how to express a k-dimensional convolution system in the form of special matrix equation, how to calculate the precise value of the matrix determinant and how to remove ...
openaire +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
This study proposes a new disturbance-observer-based adaptive distributed formation control scheme for multiple underactuated surface vehicles (USVs) subject to unknown synthesized disturbances under prescribed performance constraints. A modified sliding
Jin Li, Mingyu Fu, Yujie Xu
doaj +1 more source

