Results 101 to 110 of about 563,519 (262)

A Viscous Boundary Layer Mesh Adaptation Method and Its Application in High-Angle-of-Attack Separated Flows

open access: yesApplied Sciences
Adjoint-based mesh adaptation method serves as an effective approach to improve the predictive accuracy of aerodynamic characteristics. However, viscous boundary layer grids often encounter issues such as hanging nodes, negative volumes, and directional ...
Pengcheng Cui   +8 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Stochastic Claims Reserve in the Healthcare System: A Methodology Applied to Italian Data

open access: yesRisks
One of the challenges in the healthcare sector is making accurate forecasts across insurance years for claims reserve. Healthcare claims present huge variability and heterogeneity influenced by random decisions of the courts and intrinsic characteristics
Claudio Mazzi   +4 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Self-equilibrated residual based error estimation on 1-irregular meshes in finite elasticity

open access: yesArchives of Mechanics
We consider well-established techniques for the residual error estimation of finite element approximations applied to problems in finite elasticity.
W. Rachowicz, A. Zdunek
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Error Estimation for Adaptive Mesh Refinement in Droplet Simulations

open access: yesFluids
We present a one-dimensional shear-force-driven droplet formation model with a flux-based error estimator. The model is derived using asymptotic expansion and a front-tracking method to simulate the droplet interface.
Darsh Nathawani, Matthew Knepley
doaj   +1 more source

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