Results 91 to 100 of about 2,360,976 (284)
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Model Reduction of Parametric Differential-Algebraic Systems by Balanced Truncation
We deduce a procedure to apply balanced truncation to parameter-dependent differential-algebraic systems. For that we solve multiple projected Lyapunov equations for different parameter values to compute the Gramians that are required for the truncation ...
Jennifer Przybilla, Matthias Voigt
doaj +1 more source
Identification of dynamic systems, theory and formulation [PDF]
The problem of estimating parameters of dynamic systems is addressed in order to present the theoretical basis of system identification and parameter estimation in a manner that is complete and rigorous, yet understandable with minimal prerequisites ...
Iliff, K. W., Maine, R. E.
core +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
ERROR ESTIMATION AND ADAPTIVITY IN ELASTOPLASTICITY
Summary: A method is developed to control the parameters of a finite element computation for time-dependent material models. To evaluate discretization errors, we use a global error measure in constitutive relation based on Drucker's inequality. This error includes, over the studied time interval, the error of the finite element model and the error of ...
Gallimard, L. +2 more
openaire +3 more sources
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Control by model error estimation [PDF]
Modern control theory relies upon the fidelity of the mathematical model of the system. Truncated modes, external disturbances, and parameter errors in linear system models are corrected by augmenting to the original system of equations an 'error system'
Likins, P. W., Skelton, R. E.
core +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
CAVITY FLOW OF FLUID UNDER GRAVITY AROUND THE ANNULAR LIP ACCORDING TO THE RYABUSHINSKY SCHEME
The paper focuses on cavity flow of the ideal weight fluid around a circular cylinder using the Ryabushinsky scheme. The form of the free boundary is calculated and dependences of resistance, fluid velocity at the highest point of the cavityboundary, the
V. P. Zhitnikov, R. R. Muksimova
doaj

