Results 71 to 80 of about 2,360,976 (284)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

MATH: A Scientific Tool for Numerical Methods Calculation and Visualization

open access: yesJournal of Open Research Software, 2016
MATH is an easy to use application for various numerical methods calculations with graphical user interface and integrated plotting tool written in Qt with extensive use of Qwt library for plotting options and use of Gsl and MuParser libraries as a ...
Henrich Glaser-Opitz   +1 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

A Combination of TsHARP and Thin Plate Spline Interpolation for Spatial Sharpening of Thermal Imagery

open access: yesRemote Sensing, 2014
There have been many studies and much attention paid to spatial sharpening for thermal imagery. Among them, TsHARP, based on the good correlation between vegetation index and land surface temperature (LST), is regarded as a standard technique because of ...
Xuehong Chen   +4 more
doaj   +1 more source

BER estimation for wireless links using BPSK/QPSK modulation [PDF]

open access: yes, 2003
This paper introduces a method that computes an estimation of the bit error rate (BER) based on the RAKE receiver soft output only. For this method no knowledge is needed about the channel characteristics nor the precise external conditions.
Hurink, Johann L.   +2 more
core   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Rigid Body Motion Estimation based on the Lagrange-d'Alembert Principle

open access: yes, 2015
Stable estimation of rigid body pose and velocities from noisy measurements, without any knowledge of the dynamics model, is treated using the Lagrange-d'Alembert principle from variational mechanics.
Barany, Ernest   +3 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Asymptotic properties and approximation of Bayesian logspline density estimators for communication-free parallel computing methods

open access: yes, 2018
In this article we perform an asymptotic analysis of Bayesian parallel density estimators which are based on logspline density estimation. The parallel estimator we introduce is in the spirit of a kernel density estimator introduced in recent studies. We
Conlon, Erin   +2 more
core  

Home - About - Disclaimer - Privacy