Results 51 to 60 of about 2,360,976 (284)

An analysis of the cost of hyper-parameter selection via split-sample validation, with applications to penalized regression

open access: yes, 2019
In the regression setting, given a set of hyper-parameters, a model-estimation procedure constructs a model from training data. The optimal hyper-parameters that minimize generalization error of the model are usually unknown.
Feng, Jean, Simon, Noah
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Convergence analysis of iterative scheme and error estimation of positive solution for a fractional differential equation

open access: yesMathematical Modelling and Analysis, 2018
In this paper, we focus on the iterative scheme and error estimation of positive solutions for a class of p-Laplacian fractional order differential equation subject to Riemann-Stieltjes integral boundary condition.
Jing Wu   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Global Calibration and Error Estimation of Altimeter, Scatterometer, and Radiometer Wind Speed Using Triple Collocation

open access: yesRemote Sensing, 2020
The accuracy of wind speed measurements is important in many applications. In the present work, error standard deviations of wind speed measured by satellites and National Data Buoy Center (NDBC) buoys were estimated using triple collocation.
Agustinus Ribal, Ian R. Young
doaj   +1 more source

Mean Estimation from Adaptive One-bit Measurements

open access: yes, 2017
We consider the problem of estimating the mean of a normal distribution under the following constraint: the estimator can access only a single bit from each sample from this distribution.
Duchi, John C., Kipnis, Alon
core   +1 more source

Reliable Eigenspace Error Estimation Using Source Error Estimators

open access: yesComputational Methods in Applied Mathematics
Abstract We introduce a framework for repurposing error estimators for source problems to compute an estimator for the gap between eigenspaces and their discretizations. Of interest are eigenspaces of finite clusters of eigenvalues of unbounded nonselfadjoint linear operators with compact resolvent.
Jay Gopalakrishnan   +1 more
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Morgan-Voyce Polynomial Approach for Solution of High-Order Linear Differential-Difference Equations with Residual Error Estimation

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2016
The main aim of this study is to apply the Morgan-Voyce polynomials for the solution of high-order linear differential difference equations with functional arguments under initial boundary conditions.
Bengü Türkyılmaz   +2 more
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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