Results 61 to 70 of about 655,974 (311)
Reflection method of estimation for measurement error models [PDF]
, 2012 This paper proposes an estimation method based on the reflection of the (manifest) explanatory variable to estimate the parameters of a simple linear regression model when both response and explanatory variables are subject to measurement error (ME). The
Saqr, Anwar, Khan, Shahjahan
core
Estimation of prediction error variances via Monte Carlo sampling methods using different formulations of the prediction error variance [PDF]
, 2009 peer-reviewedCalculation of the exact prediction error variance covariance matrix is often computationally too demanding, which limits its application in REML algorithms, the calculation of accuracies of estimated breeding values and the control of ...
Veerkamp Roel F +15 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Information-Corrected Estimation: A Generalization Error Reducing Parameter Estimation Method
Entropy, 2021 Modern computational models in supervised machine learning are often highly parameterized universal approximators. As such, the value of the parameters is unimportant, and only the out of sample performance is considered.
Matthew Dixon, Tyler Ward
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Simple Statically Indeterminate Truss (Linear, Nonlinear and Stochastic Approach) [PDF]
Transactions of the VŠB-Technical University of Ostrava, Mechanical Series, 2016 This contribution deals with simple planar and statically indeterminate pin-connected truss. This truss contains 3 members. The ways and methods of derivations and solutions according to theories of 1st and 2nd order are shown.
Karel FRYDRÝŠEK
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Small area estimation: new developments and directions [PDF]
, 2002 The purpose of this paper is to provide a critical review of the main advances in small area estimation (SAE) methods in recent years. We also discuss some of the earlier developments, which serve as a necessary background for the new studies. The review
Pfeffermann, Danny
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source