Results 71 to 80 of about 531,785 (265)

ERROR ESTIMATION AND ADAPTIVITY IN ELASTOPLASTICITY

open access: yesInternational Journal for Numerical Methods in Engineering, 1996
Summary: A method is developed to control the parameters of a finite element computation for time-dependent material models. To evaluate discretization errors, we use a global error measure in constitutive relation based on Drucker's inequality. This error includes, over the studied time interval, the error of the finite element model and the error of ...
Gallimard, L.   +2 more
openaire   +3 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Speed-sensorless Control of Induction Motor Experience on Metro Vehicles

open access: yes机车电传动, 2014
Based on the principle of induction motor speed estimation, the stability of the estimation algorithm was analyzed, as well as the influence of voltage error and stator resistance error in motor model on speed estimation at very low speed condition in ...
MEI Wen-qing, LIU Yong, GAN Wei-wei
doaj  

Adaptive Prescribed Performance Fault Estimation and Accommodation for a Class of Stochastic Nonlinear Systems

open access: yesIEEE Access, 2019
This paper studies the problem of adaptive fault estimation and accommodation for a class of stochastic nonlinear systems with unknown time-varying faults.
Qing Li   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

The Comedy of Measurement Errors: Standard Error of Measurement and Standard Error of Estimation

open access: yesAdvances in Methods and Practices in Psychological Science
Testing is used to inform a range of critical decisions that help structure much of contemporary society. An unavoidable aspect of testing is that test scores are not infallible.
David J. Stanley, Jeffrey R. Spence
doaj   +1 more source

Multi-Sensor Adaptive Weighted Data Fusion Based on Biased Estimation

open access: yesSensors
In order to avoid the loss of optimality of the optimal weighting factor in some cases and to further reduce the estimation error of an unbiased estimator, a multi-sensor adaptive weighted data fusion algorithm based on biased estimation is proposed ...
Mingwei Qiu, Bo Liu
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy