Results 81 to 90 of about 783,980 (293)

Isolated methylmalonic acidemia in Mexico: Genotypic spectrum, report of two novel MMUT variants and a possible synergistic heterozygosity effect

Molecular Genetics and Metabolism Reports
Isolated methylmalonic acidemia (iMMA) is a group of monogenic metabolic disorders affecting methylmalonate and cobalamin metabolism. Five iMMA-responsible genes have been described to date: MMUT (MIM *609058), MMAA (MIM *607481, MMAB (MIM *607568 ...
Cynthia Fernández-Lainez, Marcela Vela-Amieva, Miriam Reyna-Fabián, Liliana Fernández-Hernández, Sara Guillén-López, Lizbeth López-Mejía, Miguel Ángel Alcántara-Ortigoza, Ariadna González-del Angel, Rosa Itzel Carrillo-Nieto, Enrique Ortega-Valdez, Mauricio Rojas-Maruri, Cecilia Ridaura-Sanz   +11 more
doaj   +1 more source

La expresión oral en español de los estudiantes japoneses : errores detectados en una clase de preparación para el DELE inicial [PDF]

, 2008
El analisis de errores se aplica en la ensenanza de lenguas "con el fin de que la consideracion de los datos empricos oriente la adopcion de procedimientos de ensenanza que contribuyan a agilizar el proceso de aprendizaje y a sustentar el logro de una ...
Santiago Esparaza Celorrio
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

102 errores en valoraciones de empresas [PDF]

Este documento de investigación es una recolección de 102 errores cometidos en distintas valoraciones de empresas. La mayor parte de las valoraciones que aparecen referidas en el documento proceden de valoraciones a las que el autor ha tenido acceso al ...
Fernandez, Pablo
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Errores y dificultades frecuentes al aplicar las técnicas de conteo (Frequent errors and difficulties in applying counting techniques)

Revista Digital Matemática, Educación e Internet
Los errores y dificultades frecuentes que presentan los estudiantes de Estadística I en la UDO Anzoátegui, al aplicar técnicas de conteo, se encuentran, en su mayoría, al resolver problemas de combinación y permutación.
Manuel Vicente Centeno Romero, Marvelis González Rodríguez   +1 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Errores de escritura en español en niños de tercer grado de educación primaria

Pensamiento Psicológico, 2016
Objetivo. Describir los errores en las producciones escritas de niños de tercer grado de educación primaria de escuelas públicas, teniendo en cuenta su bajo rendimiento en pruebas del Estado. Método.
Dora Elizabeth Granados Ramos, Patricia Torres Morales   +1 more
doaj  

Error analysis of economic terms in the work of Indonesian novice translation

Revista de Lenguas para Fines Específicos, 2020
There is a greater demand for a wider range of translation services that increasingly involve scientific, commercial, legal, or technical documents. Translation is no longer limited to literary works which have historically been the main focus of the ...
Indah Sari
doaj