Results 71 to 80 of about 2,136,192 (344)

Comparison of three estimators in Poisson errors-in-variables model with one covariate [PDF]

open access: yes, 2002
A structural errors-in-variables model is investigated, where the response variable follows a Poisson distribution. Assuming the error variance to be known, we consider three consistent estimators and compare their relative efficiencies by means of their
Kukush, Alexander, Shklyar, Sergiy
core   +1 more source

Likelihood Inference in the Errors-in-Variables Model

open access: yesJournal of Multivariate Analysis, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Murphy, S.A., Van Der Vaart, A.W.
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Inference on semiparametric models with discrete regressors [PDF]

open access: yes, 1993
We study statistical properties of coefficient estimates of the partially linear regression model when some or all regressors, in the unknown part of the model, are discrete. The method does not require smoothing in the discrete variables.
Delgado, Miguel A., Mora, Juan
core   +5 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Asymptotic normality of parametric part in semiparametric regression in the presence of measurement error

open access: yesAIMS Mathematics
In this study, we investigate a partially linear regression model where the covariate entering the nonparametric component is measured with error. A key challenge in such models is that the measurement error distribution is unknown, and this setting is ...
Seçil Yalaz
doaj   +1 more source

Multicollinearity and Model Misspecification

open access: yesSociological Science, 2016
Multicollinearity in linear regression is typically thought of as a problem of large standard errors due to near-linear dependencies among independent variables. This problem can be solved by more informative data, possibly in the form of a larger sample.
Christopher Winship, Bruce Western
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Optimality of Quasi-Score in the multivariate mean-variance model with an application to the zero-inflated Poisson model with measurement errors [PDF]

open access: yes, 2006
In a multivariate mean-variance model, the class of linear score (LS) estimators based on an unbiased linear estimating function is introduced. A special member of this class is the (extended) quasi-score (QS) estimator.
Kukush, Alexander   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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