Background During the final stages of differentiation of mammalian erythroid cells, the chromatin is condensed and enucleated. We previously reported that Rac GTPases and their downstream target, mammalian homolog of Drosophila diaphanous 2 (mDia2), are ...
Peng Ji +4 more
doaj +1 more source
Altered Chromatin Occupancy of Master Regulators Underlies Evolutionary Divergence in the Transcriptional Landscape of Erythroid Differentiation [PDF]
Erythropoiesis is one of the best understood examples of cellular differentiation. Morphologically, erythroid differentiation proceeds in a nearly identical fashion between humans and mice, but recent evidence has shown that networks of gene expression ...
An, Xiuli +5 more
core +2 more sources
Pathogenesis of the Erythroid Failure in Diamond Blackfan Anemia [PDF]
Author's Manuscript 2011 February 1.Diamond Blackfan anaemia (DBA) is a severe congenital failure of erythropoiesis. Despite mutations in one of several ribosome protein genes, including RPS19, the cause of the erythroid specificity is still a mystery ...
Abkowitz +56 more
core +2 more sources
Studies on the relation between heme and nucleic acid syntheses in erythroid cell. I. Effects of aminopterin and bromouracil on hemopoiesis and hemoglobin synthesis in anemic rat [PDF]
For the purpose to see how the suppression of the nucleic acid synthesis disturbs the cell specialization process the author observed the erythroid cell specialization in anemic rats by treating them with aminopterin (AP) and 5-bromouracil (BU).
Shigehisa, Morio
core +1 more source
Selective Janus kinase inhibitors exhibit different effects in murine immune aplastic anemia
HemaSphere, Volume 10, Issue 3, March 2026.
Jibran Durrani +10 more
wiley +1 more source
Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation
Clostridium perfringens α-toxin induces hemolysis of erythrocytes from various species, but it has not been elucidated whether the toxin affects erythropoiesis.
Teruhisa Takagishi +5 more
doaj +1 more source
c-Maf is indispensable for the microenvironment of definitive erythropoiesis as it forms erythroblastic islands in fetal liver [PDF]
Thesis (Ph. D. in Medical Sciences)--University of Tsukuba, (A), no.
日下部 学
core
The cytogenesis of ascitic phagocytes [PDF]
Judging from our vital observation conducted mainly by tissue culture, it was firmly demonstrated that ascitic phagocytes are not histiocytes but they are the cells closely related to monocytes and that the sites of the genesis are the milky spots of the
Fukuda, Genjiro +6 more
core +1 more source
The protective immunity afforded by CD8+ T cells against blood-stage malaria remains controversial because no MHC class I molecules are displayed on parasite-infected human erythrocytes.
Takashi Imai +6 more
doaj +1 more source
Humanized Culture Medium for Clinical Expansion of Human Erythroblasts
Ex vivo-generated erythroblasts represent alternative transfusion products. However, inclusion of bovine components in media used for their growth precludes clinical use, highlighting the importance of developing culture media based on pharmaceutical ...
Giovanni Migliaccio +6 more
doaj +1 more source

