Results 261 to 270 of about 105,167 (295)

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Erythrocyte membrane protein 3 (EMAP3) is exposed on the surface of thePlasmodium bergheiinfected red blood cell

Hernandez S, Rashpa R, Jonsdottir TK, Paoletta MS, Diaz MR, Chevalley-Maurel S, Ishizaki T, Janse CJ, Franke-Fayard B, Brochet M, Bushell ES.   +10 more
europepmc   +1 more source

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Erythrocyte Membrane: Chemical Modification

Science, 1965
Erythrocytes treated with 1-fluoro-2,4-dinitrobenzene become permeable to Na + and K + , but not to small water-soluble nonelectrolytes or hemoglobin, and eventually lyse in isotonic buffer. Erythrocytes treated with 1,5-difluoro-2,4-dinitrobenzene become permeable to Na +
H C, Berg, J M, Diamond, P S, Marfey
openaire   +2 more sources

Erythrocyte membrane transport physiology

Current Opinion in Hematology, 1997
Several transport pathways are involved in the regulation of cell volume and ion content in the human erythrocyte. Studies of these pathways have shown that K-Cl contransport and the Ca-gated K channel (Gardos channel) play an important role in the dehydration of sickle erythrocytes.
openaire   +2 more sources

Erythrocyte Membrane Elasticity and Viscosity

Annual Review of Physiology, 1987
The classical theory of elasticity (35) treats the material of a deformable body as a three-dimensional continuum in which internal stresses occur as the body is deformed by external forces acting over its surface. Although the internal stresses are caused by the displacement of atoms or molecules from an original state of equilibrium, the molecular ...
R M, Hochmuth, R E, Waugh
openaire   +2 more sources

Erythrocyte membranes: Effects of sonication

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1968
Abstract Chromatographic, ultracentrifugal and electron-microscopic studies show that sonication of red blood cell membranes breaks these membranes into small vesicles and linear fragments having intact unit membrane structures. These fragments are from 100 to 600 A in size and do not sediment under conditions usually used to define solubility.
S A, Rosenberg, J R, McIntosh
openaire   +2 more sources

Amiloride fluxes across erythrocyte membranes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1983
Amiloride is known to inhibit both the influx of Na+ and the activation of mitogenesis in many cultured cell lines. This paper describes experiments in which the permeability coefficient of amiloride was determined from measurements of tracer fluxes across human erythrocytes and resealed ghosts.
D J, Benos, J, Reyes, D G, Shoemaker
openaire   +2 more sources

Physicochemical Investigations of Erythrocyte Membranes

Nature, 1958
A SMALL drop of citrated human blood is placed on a slide next to a somewhat larger drop of Ponceau 2R and the two drops are mixed, covered with a cover glass and examined both with ordinary and polarized light. Under the double action of the dye and the hypotonicity, all the red cells become perfectly spherical with a diameter ranging from 5.0 to 5.6µ
A, TEITEL, N, MARCUS
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Surface proteins of erythrocyte membranes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1971
Abstract Diazotized sulfanilic acid labeling and trypsin digestion studies of human and bovine erythrocytes indicate that the glycoprotein of each species is the only major membrane protein which is readily accessible at the cell surface. Trypsin digestion of isolated human erythrocyte membranes under conditions identical to the erythrocyte digestion
K L, Carraway, D, Kobylka, R B, Triplett
openaire   +2 more sources