Results 41 to 50 of about 87,526 (316)

Erythrocyte membranes in metabolic syndrome

open access: yesProblems of Endocrinology, 2009
The authors discuss results of investigations into the structure and functional status of erythrocyte membranes in patients with metabolic syndrome. It is shown that the pathological process involves not only well known changes in serum lipid metabolism but also highly specialized cells, such as erythrocytes.
Elena Aleksandrovna Ananina   +12 more
openaire   +2 more sources

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

open access: yesFEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo   +4 more
wiley   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

open access: yesAdvanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang   +6 more
wiley   +1 more source

Eryptotic Phenotype in Chronic Myeloid Leukemia: Contribution of Neutrophilic Cathepsin G

open access: yesAnemia, 2012
In pathological conditions with concurrent neutrophilia, modifications of erythrocyte membrane proteins are reported. In chronic myeloid leukemia (CML), a myeloproliferative disease wherein neutrophilia is accompanied by enhanced erythrophagocytosis, we ...
Rukmini Govekar   +5 more
doaj   +1 more source

The increased erythrocyte membrane n-6/n-3 fatty acids ratio and inflammatory markers in patients with psoriasis

open access: yesIndian Journal of Rheumatology, 2019
Background: Psoriasis is a common chronic, recurrent inflammatory skin disorder. Omega-3 fatty acids exhibit low inflammatory effects, while n-6 fatty acids display high inflammatory effects.
Serap Ozer Yaman   +5 more
doaj   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im   +10 more
wiley   +1 more source

The Emerging 4D Printing of Shape‐Memory Thermomorphs for Self‐Adaptative Biomedical Implants

open access: yesAdvanced Functional Materials, EarlyView.
4D printing enables the creation of smart implants that adapt to changing conditions in the human body over time. At the core of this technology are shape‐memory thermomorphs (SMTMs). This review offers an in‐depth analysis of 4D printing with SMTMs, emphasizing the latest advancements in smart materials, stimuli, programming principles, and their ...
Aixiang Ding, Fang Tang, Eben Alsberg
wiley   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

open access: yesAdvanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu   +6 more
wiley   +1 more source

Mechanism of hypoxia-induced damage to the mechanical property in human erythrocytes—band 3 phosphorylation and sulfhydryl oxidation of membrane proteins

open access: yesFrontiers in Physiology
Introduction: The integrity of the erythrocyte membrane cytoskeletal network controls the morphology, specific surface area, material exchange, and state of erythrocytes in the blood circulation.
Qinqin Yang   +4 more
doaj   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

open access: yesAdvanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan   +4 more
wiley   +1 more source

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