Results 61 to 70 of about 680,017 (354)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Change in the fatty acids spectrum of erythrocyte in patients with chronic form of coronary heart disease in treatment by Simvastatin

Бюллетень сибирской медицины, 2012
The research of unsaturated and saturated of fatty acids (UFAand SFA) in the erythrocytes in men and women with chronic ischemic heart disease was done by the method of a gas-liquid chromatography-mass spectrometry before and after simvastatin intake ...
V. V. Novitsky, M. Yu. Kotlovsky, D. A. Kirichenko, R. S. Karpov, Yu. V. Kotlovsky, I. Yu. Yakimovich   +5 more
doaj   +1 more source

Flowcytometric assessment of fetomaternal hemorrhage during external cephalic version at term [PDF]

, 2008
External cephalic version (ECV) at term is a safe procedure and reduces the incidence of cesarean sections for breech presentation. One of the known complications, however, is an ECV-related disruption of the placental barrier and a subsequent ...
Friese, Klaus, Hermann, Christine, Kachler, Andrea, Kainer, Franz, Scholz, Christoph, Toth, Bettina, Weissenbacher, Tobias   +6 more
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Состояние периферического звена эритрона при дисплазии соединительной ткани у детей

Бюллетень сибирской медицины, 2008
Status of peripheral blood erythrocytes was studied in 51 children aged 8 to 12 years with connective tissue dysplasia (CTD). There were re vealed modifications superficial architectonics of red cells, decreased thiol groups and lipoprotein complex ...
D. A. Ponomaryova
doaj   +1 more source

The Gates Malaria Partnership: a consortium approach to malaria research and capacity development.

, 2012
Recently, there has been a major increase in financial support for malaria control. Most of these funds have, appropriately, been spent on the tools needed for effective prevention and treatment of malaria such as insecticide-treated bed nets, indoor ...
Bhasin, Amit, Greenwood, Brian, Targett, Geoffrey   +2 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

ИЗМЕНЕНИЯ ОПТИЧЕСКИХ ПАРАМЕТРОВ КРОВИ У ПАЦИЕНТОВ С ЦИРРОЗАМИ ПЕЧЕНИ РАЗЛИЧНОЙ СТЕПЕНИ ТЯЖЕСТИ

Архивъ внутренней медицины, 2014
The optical parameters of red blood cells and serum from patients with different classes of liver cirrhosis by Child–Pugh were examined by atomic force microscopy, dielectrophoresis, spectral ellipsometry, terahertz and Raman-spectroscopy.
М. В. Кручинина, М. И. Воевода, С. А. Курилович, А. А. Громов, В. А. Баум, Е. Г. Немцова, Е. В. Логвиненко, Н. А. Ковалькова, В. М. Генералов, Б. Н. Зайцев, В. Н. Кручинин, С. В. Рыхлицкий, Б. А. Князев, В. В. Герасимов, А. Г. Покровский, В. О. Пустыльняк, С. В. Чересиз, Г. Р. Сакаева, А. И. Корбут, В. Д. Анцыгин   +19 more
doaj   +1 more source

The Diverse Neuromuscular Spectrum of VPS13A Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger, Evamaria Riedel, Marie Hackenberg, Alexander Mensch, Stefanie Beck‐Woedl, Joohyun Park, Tobias B. Haack, Bernhard Haslinger, Jan Kirschke, Holger Prokisch, Andreas Hermann, Christian Mawrin, Adrian Danek, Benedikt Schoser, Kevin Peikert, Marcus Deschauer, Isabell Cordts   +16 more
wiley   +1 more source

An Immunomodulatory Zinc‐Alum/Ovalbumin Nanovaccine Boosts Cancer Metalloimmunotherapy Through Erythrocyte‐Assisted Cascade Immune Activation

Advanced Science
Cancer therapeutic vaccines are powerful tools for immune system activation and eliciting protective responses against tumors. However, their efficacy has often been hindered by weak and slow immune responses.
Jing Zhao, Lingxiao Zhang, Pin Li, Shanbiao Liu, Shiyi Yu, Zheng Chen, Mingjian Zhu, Shangzhi Xie, Daishun Ling, Fangyuan Li   +9 more
doaj   +1 more source