Results 61 to 70 of about 456,266 (310)

A cross-sectional study of serum B12 and folate level in alcoholics and nonalcoholics

open access: yesMuller Journal of Medical Sciences and Research, 2022
Introduction: One of the world's most important public health and global health issues is alcoholism. In terms of illness burden, alcohol is the world's third leading cause of death.
S Myilsamy   +3 more
doaj   +1 more source

Imaging morphological details and pathological differences of red blood cells using tapping-mode AFM [PDF]

open access: yes, 2004
The surface topography of red blood cells (RBCs) was investigated under nearphysiological conditions using atomic force microscopy (AFM). An immobilization protocol was established where RBCs are coupled via molecular bonds of the membrane glycoproteins ...
Berg, Jörg   +9 more
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Effect of sub-lethal lead exposure at different salinities on osmoregulation and hematological changes in tilapia, Oreochromis niloticus

open access: yesArchives of Polish Fisheries, 2017
The objectives of this study were to evaluate the effects of sub-lethal lead concentrations on serum osmolality, Na+ and Cl− levels, and hematological parameters in Nile tilapia, Oreochromis niloticus (L.) at different salinity levels.
Adhim Ma’dan Haikal   +4 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Türk Kızılay’ı Bölge Kan Merkezlerinde Kan Ürünleri İmha Oranı ve Nedenleri Üzerine Tanımlayıcı Retrospektif Bir Çalışma

open access: yesAnkara Sağlık Bilimleri Dergisi
Amaç: Kan, insan hayatı için vazgeçilmez ve değerli sıvılardan biridir. Bu çalışmanın amacı Türk Kızılay’ı Kan Hizmetleri Genel Müdürlüğüne bağlı 18 bölge kan merkezinde üretilen ve imha edilen kan ürünlerinin miktarını ve imha nedenlerini ortaya ...
Yasemin Aslan, Beyza Yilmaz
doaj   +1 more source

Pneumoccal Hemolysin [PDF]

open access: yes, 1971
The purposes of this report are to describe a method of preparing a potent crude pneumococcal hemolysin, to define some of it characteristics, and to describe the effects of its administration to ...
Shumway, Clare N.
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Efficacy of Vitazal® in foals with anemia syndrome

open access: yesTheoretical and Applied Veterinary Medicine, 2020
Syndrome of anemia in foals manifests itself in the first weeks of their life, and occurs because of oxygen deficiency and excess of carbon dioxide after birth, and caused by a deficiency of trace minerals (iron, copper, cobalt, zinc, iodine, selenium ...
V. I. Holovakha   +4 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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