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ВЛИЯНИЕ ОБЩЕГО ОХЛАЖДЕНИЯ ГОМОЙОТЕРМНОГО ОРГАНИЗМА НА ЭРИТРО- И ЛЕЙКОЦИТАРНЫЕ ПОКАЗАТЕЛИ КРОВИ
Цель – изучить реакции эритро- и лейкоцитарного звеньев крови крыс на действие общей иммерсионной гипотермии (ИГ). Методы. Модель ИГ в тесте «вынужденное плавание» в воде при 0°С (5 мин до 27°С).
V. V. Lomako+2 more
doaj +1 more source
Following red blood cells in a pulmonary capillary [PDF]
The red blood cells or erythrocytes are biconcave shaped cells and consist mostly in a membrane delimiting a cytosol with a high concentration in hemoglobin. This membrane is highly deformable and allows the cells to go through narrow passages like the capillaries which diameters can be much smaller than red blood cells one. They carry oxygen thanks to
arxiv +1 more source
Storage of Erythrocytes Induces Suicidal Erythrocyte Death
Background/Aims: Similar to apoptosis of nucleated cells, red blood cells (RBC) can undergo suicidal cell death - called eryptosis. It is characterized by cell shrinkage and phosphatidylserine translocation. Eryptosis is triggered by an increase of intracellular calcium concentration due to activation of nonselective cation channels.
Lang, Elisabeth+11 more
openaire +5 more sources
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Effect of acute experimental aluminum poisoning on hematologic parameters [PDF]
Having in mind the presence of aluminum in industry, as well as in households, we wanted to define changes in the number of erythrocytes and aluminum content in the plasma and erythrocytes following acute aluminum poisoning under experimental ...
Milovanović J.+9 more
doaj +1 more source
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang+10 more
wiley +1 more source
Background/Aims: Erythrocytes may enter eryptosis, a suicidal death characterized by cell shrinkage and phosphatidylserine exposure at the erythrocyte outer membrane.
Mehrdad Ghashghaeinia+11 more
semanticscholar +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
Mechanisms and Significance of Eryptosis, the Suicidal Death of Erythrocytes
Eryptosis, the suicidal death of erythrocytes, is characterized by erythrocyte shrinkage, blebbing, and phospholipid scrambling of the cell membrane. Eryptosis is triggered by increased cytosolic Ca2+ activity, which may result from Ca2+ entry through ...
F. Lang, S. Qadri
semanticscholar +1 more source
FUSION OF INTACT HUMAN ERYTHROCYTES AND ERYTHROCYTE GHOSTS [PDF]
Sendai virus is able to induce the fusion of human erythrocytes. Bivalent cations or ATP are not essential for polyerythrocyte formation. High fusion indices were obtained when Sendai virus was added to cells incubated in the presence of both EDTA and iodoacetic acid.
Hava Peretz+3 more
openaire +3 more sources