Clinical significance of stratifying prostate cancer patients through specific circulating genes
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian+12 more
wiley +1 more source
Fatty acid composition of brain, retina, and erythrocytes in breast- and formula-fed infants.
Breast-fed infants score better on visual and developmental tests than do formula-fed infants and this has been related to higher concentrations of erythrocyte docosahexaenoic acid (DHA, 22:6 omega 3). This prompted an investigation into the relationship
M. Makrides+4 more
semanticscholar +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Pairwise comparison of treatment levels in functional analysis of variance with application to erythrocyte hemolysis [PDF]
Motivated by a practical need for the comparison of hemolysis curves at various treatment levels, we propose a novel method for pairwise comparison of mean functional responses. The hemolysis curves - the percent hemolysis as a function of time - of mice erythrocytes (red blood cells) by hydrochloric acid have been measured among different treatment ...
arxiv +1 more source
On the cytoadhesion of Plasmodium vivax-infected erythrocytes.
BACKGROUND Plasmodium falciparum and Plasmodium vivax are responsible for most of the global burden of malaria. Although the accentuated pathogenicity of P.
B. O. Carvalho+19 more
semanticscholar +1 more source
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda+15 more
wiley +1 more source
Hematimetria manual e automática em jaguatiricas (Leopardus pardalis - Linnaeus, 1758)
RESUMO Aparelhos de automação, cujo uso está estabelecido na hematologia dos animais domésticos, ainda não são empregados rotineiramente em felídeos selvagens.
T.D.P. Silva+6 more
doaj +1 more source
Profile of retinal vasculitis in a tertiary eye care center in Eastern India
Aims: To provide a fact file on the etiology, clinical presentations and management of retinal vasculitis in Eastern India. Materials and Methods: Retrospective, record based analysis of retinal vasculitis cases in a tertiary care center in Eastern India
Kumar Saurabh+3 more
doaj +1 more source
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla+4 more
wiley +1 more source
Double anterior chamber in a patient with glaucoma and microspherophakia
We report the case of a 16-year-old woman with microspherophakia and secondary open angle glaucoma. The patient presented with a membrane dividing the anterior chamber into two segments without edema or Descemet′s membrane detachment.
Hamid Khakshoor+4 more
doaj +1 more source