Results 111 to 120 of about 62,107 (294)
Macrophages support pathological erythropoiesis in Polycythemia Vera and Beta-Thalassemia [PDF]
, 2014 Regulation of erythropoiesis is achieved by integration of distinct signals. Among these, macrophages are emerging as erythropoietin-complementary regulators of erythroid development, particularly under stress conditions. We investigated the contribution
Abdel-Wahab, Omar +15 more
core +1 more source
Journal of Magnetic Resonance Imaging, EarlyView.ABSTRACT Background Noninvasive quantitative assessment of marrow recovery after curative therapies such as total marrow irradiation (TMI) and bone marrow transplantation (BMT) remain poorly defined, particularly in sickle cell disease (SCD). Purpose To evaluate MRI‐derived proton density fat fraction (PDFF) as a biomarker of marrow recovery following ...
Malakeh Malekzadeh +12 more
wiley +1 more source
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Objectives Anaemia impairs daily activities and quality of life in patients with paediatric‐onset inflammatory bowel disease (PIBD). This study aimed to investigate the prevalence of anaemia at PIBD‐diagnosis and the following 5 years. Furthermore, anaemia subtypes and the association between anaemia and disease activity were assessed over ...
Julie Rahbek Norup +3 more
wiley +1 more source
Neuroprotection, EarlyView.Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang +6 more
wiley +1 more source
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To evaluate the effectiveness of objective audiological and vestibular assessments in detecting functional changes associated with vitamin B12 deficiency. Data Sources A comprehensive literature search was conducted in PubMed, Scopus, Web of Science, and EMBASE databases.
Nesmah Zainab +2 more
wiley +1 more source
Initiation of erythropoiesis by BFU-E cells
, 2015 Erythropoiesis is the process of red blood cell production in the bone marrow. Terminal stages of human erythropoiesis occur in multicellular structures called erythroblastic islands (EBIs).
Volpert Vitaly +3 more
core +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij +11 more
wiley +1 more source
Store-operated Ca2+ Channels Are Involved In Erythropoiesis
, 2019 Erythropoiesis is the process which produces red blood cells from erythropoietic stem cells. Ca2+ is a fundamental second messenger which regulates dynamic cellular processes, such as, cell differentiation, proliferation, cytoskeletal rearrangement, and ...
Park, Chan Young +5 more
core
CAMP/PKA-mediated regulation of erythropoiesis
, 2003 The role of cyclic AMP (cAMP) as second messenger in erythropoiesis has been suggested in the early 1980s. However, careful analysis showed that cAMP is not generated in direct response to the main erythropoiesis-controlling cytokines such as ...
Drayer, AL, Vellenga, E, Boer, AK
core +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Objective This study evaluates the procedural characteristics, complications, and outcomes of intrauterine transfusion (IUT) for fetal anemia caused by parvovirus B19 infection during the 2023–2024 epidemic in Northwestern Europe. Method This multicenter observational study included all fetuses undergoing IUT for proven parvovirus B19‐induced ...
Banu Özbakir +6 more
wiley +1 more source