Results 111 to 120 of about 60,520 (262)

Erythropoiesis-stimulating agents for anaemia in chronic heart failure patients (Intervention Review)

, 2010
Background: Chronic heart failure (CHF) is a leading cause of morbidity and mortality worldwide. Anaemia is a common (12-55%) co-morbid condition and is associated with worsening symptoms and increased mortality.
Kotecha, D (15525671), Ngo, K (15525668), Walters, JAE (15494048), van Veldhuisen, DJ (15533897), Palazzuoli, A (15533894), Manzano, L (15525674), Flather, M (15525677)   +6 more
core  

Prognostic Significance of Peripheral Blood Neutrophil‐To‐Lymphocyte Ratio (NLR), Monocyte‐To‐Lymphocyte Ratio (MLR), and Platelet‐To‐Lymphocyte Ratio (PLR) in Patients With Multiple Myeloma: A Retrospective Cohort Study

Journal of Clinical Laboratory Analysis, EarlyView.
This graphical abstract illustrates the prognostic significance of systemic inflammatory markers in Multiple Myeloma (MM). The left panel depicts the immunosuppressive tumor microenvironment, where abundant neutrophils and M2 macrophages promote MM cell survival while lymphocytes are depleted.
Lihong Zhang, Bing Ma, Jingyu Zhang
wiley   +1 more source

Effect of hepatitis C virus infection on erythropoiesis in patients on hemodialysis

, 2013
Chadi Saifan, Elie El-Charabaty, Morton Kleiner, Suzanne El-SayeghDepartment of Medicine, Division of Nephrology, Staten Island University Hospital, Staten Island, NY, USABackground: Erythropoietin is a hormone that regulates erythropoiesis and is mainly
Kleiner M, El-Sayegh S, Saifan C, El-Charabaty E   +3 more
core  

Erythropoiesis-stimulating agents for the treatment of chemotherapy-induced anemia: comparisons from real-world clinical experience

, 2014
Analia Rodriguez Garzotto,1 Oliver Heine,2 Matthew Turner,3 Francisco Rebollo Laserna,4 Andreas Lorenz5 1Hospital Universitario 12 de Octubre, Ctra Andalucía, Madrid, Spain; 2Zentralklinikum Suhl, Suhl, 3Sandoz International GmbH, Holzkirchen ...
Rebollo Laserna F, Turner M, Heine O, Lorenz A, Rodriguez Garzotto A   +4 more
core  

Impact of Anemia and Comorbidity Burden on Disease Progression and Outcomes in Chronic Kidney Disease

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluates the prognostic value of immuno‐hematological markers—including anemia status, RDW, hemoglobin levels, and multimorbidity burden—in predicting chronic kidney disease (CKD) progression among adult patients. Findings reveal that anemia and the presence of ≥ 2 comorbidities strongly amplify the risk of CKD progression and ...
Collince Odiwuor Ogolla, Stanslaus Musyoki, Lucy W. Karani, Phidelis Maruti   +3 more
wiley   +1 more source

Development and Validation of a Nomogram Based on Red Blood Cell and Reticulocyte Parameters for Differentiating Thalassemia Trait From Iron Deficiency Anemia

Journal of Clinical Laboratory Analysis, EarlyView.
Thalassemia trait (TT) and iron deficiency anemia (IDA) are the primary causes of microcytic hypochromic anemia with overlapping hematological features, making their differential diagnosis challenging, so this study developed and validated a nomogram integrating red blood cell (RBC) count, mean corpuscular volume (MCV), reticulocyte percentage (RET ...
Yong Chen, Yazhen Mao, Jie Liu, Yice Lin, Dandan Chen   +4 more
wiley   +1 more source

MRI Proton Density Fat Fraction as a Biomarker of Marrow Recovery Following Organ‐Sparing Total Marrow Irradiation in Sickle Cell Disease

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Noninvasive quantitative assessment of marrow recovery after curative therapies such as total marrow irradiation (TMI) and bone marrow transplantation (BMT) remain poorly defined, particularly in sickle cell disease (SCD). Purpose To evaluate MRI‐derived proton density fat fraction (PDFF) as a biomarker of marrow recovery following ...
Malakeh Malekzadeh, Hemendra Ghimire, Ji Eun Lim, Srideshikan S. Madabushi, Weidong Hu, Marco Andrea Zampini, Kazuki Fujita, Raghda Fouda, Guy Storme, Joo Song, Bihong T. Chen, Anna Pawlowska, Susanta K. Hui   +12 more
wiley   +1 more source

Regulation of platelet count by erythropoiesis-stimulating agents – iron axis in hemodialysis patients

, 2016
Kiyomi Koike,1,2 Kei Fukami,1 Atsushi Kawaguchi,2 Kazumasa Shimamatsu,3 Sho-ichi Yamagishi,4 Seiya Okuda1 1Division of Nephrology, Department of Medicine, Kurume University School of Medicine, Kurume, 2The Biostatistics Center, Kurume University, Kurume,
Kawaguchi A, Fukami K, Yamagishi SI, Okuda S, Koike K, Shimamatsu K   +5 more
core  

Stress erythropoiesis in atherogenic mice

, 2020
© The Author(s) 2020.Bone marrow erythropoiesis is mainly homeostatic and a demand of oxygen in tissues activates stress erythropoiesis in the spleen. Here, we show an increase in the number of circulating erythrocytes in apolipoprotein E−/− mice fed a ...
Aranda, Ana, Castrillo, Antonio, Orizaola, Marta C., Alemany, Susana, Sánchez, Ángela, Rodriguez-Muñoz, Diego   +5 more
core   +1 more source

Anaemia in patients diagnosed with paediatric‐onset inflammatory bowel disease: A Danish nationwide cohort study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Anaemia impairs daily activities and quality of life in patients with paediatric‐onset inflammatory bowel disease (PIBD). This study aimed to investigate the prevalence of anaemia at PIBD‐diagnosis and the following 5 years. Furthermore, anaemia subtypes and the association between anaemia and disease activity were assessed over ...
Julie Rahbek Norup, Sabine Jansson, Vibeke Wewer, Mikkel Malham   +3 more
wiley   +1 more source