Results 91 to 100 of about 55,366 (304)
International Journal of Cancer, EarlyView.ABSTRACT The recently published ONKOPEDIA guideline on myelofibrosis, issued under the auspices of the German Society of Hematology and Oncology (DGHO), provides an updated, evidence‐based framework for the diagnosis and management of this rare, chronic myeloproliferative neoplasm.
Martin Griesshammer +8 more
wiley +1 more source
Erythropoiesis and iron kinetics.
, 1978 Analysis of the relationship between erythropoiesis and iron kinetics in ...
CAZZOLA, MARIO +7 more
core +1 more source
The Shape Shifting Story of Reticulocyte Maturation
Frontiers in Physiology, 2018 The final steps of erythropoiesis involve unique cellular processes including enucleation and reorganization of membrane proteins and the cytoskeleton to produce biconcave erythrocytes. Surprisingly this process is still poorly understood.
Elina Ovchynnikova +7 more
doaj +1 more source
The regulation of stem cell fate and its application in neural regeneration
Interdisciplinary Medicine, EarlyView.Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He +3 more
wiley +1 more source
Erythropoiesis stimulating agents approaches to modulate activity
, 2013 Angus M Sinclair Amgen Inc, Thousand Oaks, CA, USA Abstract: Recombinant human erythropoietin (rHuEPO), such as the approved agents epoetin alfa and epoetin beta, has been used successfully for over 20 years to treat anemia in millions of patients ...
Sinclair AM
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Reconceptualizing Aplastic Anemia—Seed, Worm, Soil
Journal of Clinical Laboratory Analysis, EarlyView.Aplastic anemia (AA) encompasses a group of hematological syndromes often misdiagnosed, resulting in a decrease in the overall blood cell count and representing a form of bone marrow failure. We reinterpret AA based on the “seed, worm, and soil” doctrine.
Xintong Xu +4 more
wiley +1 more source
Using the Zebrafish as a Genetic Model to Study Erythropoiesis
, 2021 Vertebrates generate mature red blood cells (RBCs) via a highly regulated, multistep process called erythropoiesis. Erythropoiesis involves synthesis of heme and hemoglobin, clearance of the nuclei and other organelles, and remodeling of the plasma ...
Mengying Chen, Caiyong Chen, Yuhan Zhang
core +1 more source
Hematopoietic Cytokine Gene Duplication in Zebrafish Erythroid and Myeloid Lineages
Frontiers in Cell and Developmental Biology, 2018 Hematopoiesis is a precisely orchestrated process regulated by the activity of hematopoietic cytokines and their respective receptors. Due to an extra round of whole genome duplication during vertebrate evolution in teleost fish, zebrafish have two ...
Jana Oltova +3 more
doaj +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.ABSTRACT Background Hemoglobin British Columbia is a rare high‐oxygen‐affinity β‐globin variant caused by the HBB:c.304G>A substitution. Its detection is exceptionally uncommon, particularly in the Middle East, and may lead to diagnostic pitfalls when relying solely on hemoglobin separation techniques.
Kimia Fathalizade +5 more
wiley +1 more source
SAMD14 Mechanisms in Stress Erythropoiesis
, 2023 Red blood cells (RBCs) essential for tissue oxygenation are generated by the process of erythropoiesis. Any decrease in the RBCs or the oxygen-carrying molecule hemoglobin leads to anemia, affecting nearly 1.62 billion people worldwide.
Ray, Suhita
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