Results 101 to 110 of about 62,107 (294)

Delineation of erythropoietic intermediates by flow cytometry

Frontiers in Hematology
Erythropoiesis occurs through specification from multipotent progenitors to erythroid restricted potential, expansion of erythroid progenitors, and terminal maturation of precursors to red blood cells.
Kathleen E. McGrath
doaj   +1 more source

Hematological and Genotoxic Effects of Subchronic Oral Exposure to a Mancozeb‐Based Fungicide in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo, Natanael Vaz Crisóstomo Peixoto, Paula Soares Nakamura, Cecília Müller Wodzik, Lucas Ribeiro Maia dos Santos, Fábio Vieira de Andrade Borges, Lara Cândida de Sousa Machado, Jéssica Gardone Vitório, Renata Mazaro e Costa, Mônica Rodrigues Ferreira Machado, Walter Dias Júnior   +10 more
wiley   +1 more source

Histone modifications in the regulation of erythropoiesis

Introduction The pathogenesis of anemia and other erythroid dysphasia are mains poorly understood, primarily due to limited knowledge about the differentiation processes and regulatory mechanisms governing erythropoiesis.
Hengchao Zhang, Lei Sun, Xiuyun Wu, Erxi Xia, Yan Hou, Hongdi Xu, Linru Gao, Ying Cheng   +7 more
core   +1 more source

Molecular insights into stress erythropoiesis

, 2007
Purpose of review: In addition to its essential role in baseline erythropoiesis, the hormone erythropoietin drives the erythropoietic response to hypoxic stress.
Socolovsky, Merav
core   +1 more source

Heme oxygenase-1 deletion affects stress erythropoiesis. [PDF]

, 2011
BACKGROUND:Homeostatic erythropoiesis leads to the formation of mature red blood cells under non-stress conditions, and the production of new erythrocytes occurs as the need arises.
David K Stevenson, Cao Yu-An, Stevenson David K., Christopher H. Contag, Contag Christopher H., Richard Luong, Sophie Kusy, Christopher H Contag, Kusy Sophie, Ronald J Wong, Ronald J. Wong, Yu-An Cao, Luong Richard, Wong Ronald J., David K. Stevenson   +14 more
core   +1 more source

Flow Cytometry‐Guided Diagnosis of Cortical T‐Lymphoblastic Lymphoma Presenting With a Massive Mediastinal Mass and Borderline Bone Marrow Involvement

Journal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background T‐cell lymphoblastic lymphoma (T‐LBL) and T‐cell acute lymphoblastic leukemia (T‐ALL) are considered a single biological entity, distinguished primarily by the extent of bone marrow infiltration. This distinction becomes diagnostically challenging in patients with borderline marrow blast counts and predominantly extramedullary ...
Chen Glait‐Santar, Yakir Moshe, Itzhaki‐Alfia Ayelet, Ben‐Zion Katz   +3 more
wiley   +1 more source

Erythropoiesis and the normal red cell

, 2010
Erythropoiesis is a highly regulated, multistep process in which stem cells, after a series of amplification divisions, generate multipotential progenitor cells, then oligo- and finally unilineage erythroid progenitors, and then morphologically ...
Anna Rita Migliaccio, Thalia Papayannopoulou   +1 more
core   +1 more source

New insights into iron regulation and erythropoiesis [PDF]

, 2015
Purpose of reviewIron homeostasis and erythropoiesis regulate each other to ensure optimal delivery of oxygen and iron to cells and tissues. Defining the mechanisms of this crosstalk is important for understanding the pathogenesis of common conditions ...
Nemeth, Elizabeta, Kim, Airie
core   +1 more source

Evaluation of Different Methods of Haemoglobin Estimation Among Malaria‐Infected Patients

Journal of Clinical Laboratory Analysis, EarlyView.
This study compared haemoglobin concentrations measured with an automated Full Blood Count (Sysmex XN‐550) analyzer, the cyanmethemoglobin method, and a portable Hb meter (HemoCue Hb 301) in 100 patients with malaria. The three methods showed good agreement and broadly comparable measurements, though small systematic differences were observed.
Mina Ofosu, Jessica Ntiamoah, Patricia Sam Barko, Prince Elikem Torli   +3 more
wiley   +1 more source

Genetic and Clinical Characteristics of Thalassemia Trait and Construction of LASSO‐Based Model for Its Differentiating From Iron Deficiency Anemia in Northern China

Journal of Clinical Laboratory Analysis, EarlyView.
This study revealed a β‐thalassemia‐trait‐dominated genetic spectrum in Northern‐Chinese patients with microcytic hypochromic anemia, with _αSEA/αα, HBB:c.316_197C>T and HBB:c.124_127delTTCT being the most prevalent α‐ and β‐globin genotypes. Using LASSO regression, we constructed a nomogram based on four routine complete‐blood‐count parameters (RBC ...
Wen‐jie Yu, Feng‐qi Zhang, Jia‐feng Niu, Rui Ma, Yin‐ting Ma, Guang‐ping Li, Yan Long   +6 more
wiley   +1 more source