Results 121 to 130 of about 55,366 (304)
Andrology, EarlyView.ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani +8 more
wiley +1 more source
Methods to assess iron and iodine status
, 2008 Four methods are recommended for assessment of iodine nutrition: urinary iodine concentration, the goitre rate, and blood concentrations of thyroid stimulating hormone and thyroglobulin.
Zimmermann, Michael B., Zimmermann, M.B.
core +1 more source
Defining the Processes Regulating Stress Erythropoiesis [PDF]
, 2020 The current thesis aimed at broadening our understanding of the processes governing stress erythropoiesis. Phenylhydrazine-induced haemolytic anaemia was utilised as a mouse model of acute stress erythropoiesis.
Colonne, Chanukya
core
Developmental Trends in Serum Iron, Transferrin, and Transferrin Saturation From Birth to 12 Months
Acta Paediatrica, EarlyView.ABSTRACT Aim There is a need for updated reference intervals for iron status biomarkers during infancy. This study aimed to investigate reference interval trends and diurnal variation of iron, transferrin, and transferrin saturation in infants subjected to delayed cord clamping at birth (DCC). Methods Data analysis from population‐based Swedish studies,
Sara Marie Larsson +5 more
wiley +1 more source
Role of the kidney in erythropoiesis
, 1960 There was a marked reduction in erythropoiesis and hemoglobin synthesis in the nephrectomized dog as compared to the normal intact animal even when azotemia was reduced to a low level by intermittent peritoneal lavage.
Arthur Grollman, Wadi Suki
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British Journal of Haematology, EarlyView.Targeted next‐generation sequencing combined with a structured interpretative framework integrating gene–disease validity, population data, computational predictions, ACMG criteria and structural modelling enabled prioritisation of rare variants in idiopathic erythrocytosis, highlighting the genetic heterogeneity and biological complexity underlying ...
Alessandra Giannella +21 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley +1 more source
Molecular insights into stress erythropoiesis
, 2007 Purpose of review: In addition to its essential role in baseline erythropoiesis, the hormone erythropoietin drives the erythropoietic response to hypoxic stress.
Socolovsky, Merav
core +1 more source
Cancer Science, EarlyView.Schematic illustration showing how CRC‐associated ADSC‐derived CCL8 promotes colorectal cancer cell migration through ERK/HIF‐1α signaling in a 3D coculture platform. ABSTRACT This study aimed to recapitulate adipose‐tumor interactions within the colorectal cancer (CRC) tumor microenvironment (TME) and to elucidate the role of adipose‐derived stem ...
Jeong‐Eun Yun +7 more
wiley +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background Erythropoietic protoporphyria (EPP) is a rare genetic disorder characterized by severe phototoxic reactions that occur within minutes of light exposure. In clinical studies, afamelanotide has been shown to prolong pain‐free sun exposure, improve quality of life, and reduce the frequency and severity of phototoxic reactions ...
Magdalena Seidl‐Philipp +9 more
wiley +1 more source