Results 151 to 160 of about 121,038 (379)

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Imbalance of erythropoiesis and iron metabolism in patients with thalassemia

International Journal of Medical Sciences, 2019
Aim: This study aimed to evaluate the imbalance of erythropoiesis and iron metabolism in patients with thalassemia. Methods: 192 patients with non-transfusion-dependent thalassemia (NTDT), 94 patients with transfusion-dependent thalassemia (TDT) and 101 ...
Yumei Huang, Yu Lei, Rongrong Liu, Jiaodi Liu, Gaohui Yang, Zhifu Xiang, Yu-zhen Liang, Y. Lai   +7 more
semanticscholar   +1 more source

Novel LPIN2 mutations in Majeed syndrome induce NF‐κB pathway activation

Rheumatology &Autoimmunity, EarlyView.
This study identifies novel LPIN2 mutations in Majeed syndrome that induce NF‐κB pathway activation, linking defective LPIN2 function to aberrant inflammation in this rare autoinflammatory disorder.
Yibing Han, Renmei Cai, Yuanxuan Ma, Shiguo Liu, Bin Liu   +4 more
wiley   +1 more source

Bone marrow characterization in sickle cell disease: inflammation and stress erythropoiesis lead to suboptimal CD34 recovery [PDF]

, 2019
Alexis Leonard, Aylin Bonifacino, Venina Marcela Dominical, Min Luo, Juan J. Haro‐Mora, Selami Demirci, Naoya Uchida, Francis J. Pierciey, John F. Tisdale   +8 more
openalex   +1 more source

Exposure to hypoxia causes stress erythropoiesis and downregulates immune response genes in spleen of mice [PDF]

, 2021
Haijing Wang, Daoxin Liu, Pengfei Song, Feng Jiang, Xiangwen Chi, Tongzuo Zhang   +5 more
openalex   +1 more source

Embryonal erythropoiesis and aging exploit ferroptosis

Redox Biology, 2021
Hao Zheng, Li Jiang, T. Tsuduki, M. Conrad, S. Toyokuni   +4 more
semanticscholar   +1 more source

Free Foetal Haemoglobin in Severe Early‐Onset Foetal Growth Restriction: A Prospective Multi‐Centre Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess foetal circulating free foetal haemoglobin (fHbF) levels and heme defences, correlated to foetal circulatory biometry and foetal sex in severe early‐onset foetal growth restriction (FGR). Design, Setting and Population A prospective study severe early‐onset foetal growth restriction pregnancies with close clinical ...
Adam Brook, Georgia Baynes, Jonathan Scargill, Angelos Evangelinos, Charlotte Brennan‐Richardson, Freya Dow, Yuval Ginsberg, Tal Weissbach, Jana Brodszki, Eva Hansson, Anke Diemert, Kurt Hecher, Katarzyna Maksym, Neil Marlow, Rebecca N. Spencer, Anna L. David, Stefan R. Hansson, Paul Brownbill   +17 more
wiley   +1 more source

Research opportunities in loss of red blood cell mass in space flight [PDF]

Decreases of red blood cell mass and plasma volume have been observed consistently following manned space flights. Losses of red cell mass by United States astronauts have averaged 10 to 15% (range: 2 to 21%).
Fisher, K. D., Talbot, J. M.
core   +1 more source

Thresholds of iron markers for iron deficiency erythropoiesis—finding of the Japanese nationwide dialysis registry [PDF]

, 2015
Takayuki Hamano, Naohiko Fujii, Terumasa Hayashi, Hiroyasu Yamamoto, Kunitoshi Iseki, Yoshiharu Tsubakihara   +5 more
openalex   +1 more source

Sphingolipid-mediated inflammatory signaling leading to autophagy inhibition converts erythropoiesis to myelopoiesis in human hematopoietic stem/progenitor cells

Cell Death and Differentiation, 2018
Elevated levels of the pro-inflammatory cytokine tumor necrosis factor-α (TNFα) inhibit erythropoiesis and cause anemia in patients with cancer and chronic inflammatory diseases.
M. Orsini, Sébastien Chateauvieux, J. Rhim, A. Gaigneaux, D. Cheillan, C. Christov, M. Dicato, F. Morceau, M. Diederich   +8 more
semanticscholar   +1 more source