Results 121 to 130 of about 144,316 (318)

Identification of β‐galactosidases along the secretory pathway of Nicotiana benthamiana that collectively hamper engineering of galactose‐extended glycans on recombinant glycoproteins

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Glycosylation is an important aspect for many biopharmaceuticals, including vaccines against parasitic helminths. Plants, especially Nicotiana benthamiana, have proven to be excellent production hosts for biopharmaceuticals with tailor‐made glycosylation.
Alex van der Kaaij   +7 more
wiley   +1 more source

Dynamic regulation of erythropoiesis: A computer model of general applicability [PDF]

open access: yes
A mathematical model for the control of erythropoiesis was developed based on the balance between oxygen supply and demand at a renal oxygen detector which controls erythropoietin release and red cell production.
Leonard, J. I.
core   +1 more source

Symmetric signaling by an asymmetric 1 erythropoietin : 2 erythropoietin receptor complex [PDF]

open access: yes, 2008
Thesis (M. Eng.)--Massachusetts Institute of Technology, Biological Engineering Division, 2008.Includes bibliographical references (p. 43-46).One erythropoietin molecule binds asymmetrically to two identical receptor monomers via erythropoietin site 1 ...
Zhang, Yingxin
core  

A case of anaphylaxis to gelatin included in erythropoietin products [PDF]

open access: bronze, 1999
Masahiro Sakaguchi   +2 more
openalex   +1 more source

The Discovery of Erythropoietin

open access: yesASAIO Journal, 1993
A personal vignette of life as a resident and fellow at the Yale New Haven Hospital in the early 1950s follows. John Peters and his associates created a superb renal center at Yale New Haven, and they instilled in me a respect for quantitative measurements and a love for simple physiologic concepts. The environment was ideal for clinical and laboratory
openaire   +3 more sources

Posttranslational modifications of heterologous proteins expressed in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
Summary The success of Nicotiana benthamiana as a workhorse for heterologous protein production is closely linked to its accessibility and tolerance to genetic manipulation, allowing efficient engineering of posttranslational protein modifications (PTMs) that are critical for the function and stability of heterologous proteins.
Kathrin Göritzer   +2 more
wiley   +1 more source

Feasibility of commercial space manufacturing, production of pharmaceuticals. Volume 1: Executive summary [PDF]

open access: yes
The feasibility of the commercial manufacturing of pharmaceuticals in space is examined. The method of obtaining pharmaceutical company involvement, laboratory results of the separation of serum proteins by the continuous flow electrophoresis process ...

core   +1 more source

The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]

open access: yes, 2006
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core   +1 more source

High Plasma Erythropoietin Levels are Associated With Prolonged Coma Duration and Increased Mortality in Children With Cerebral Malaria [PDF]

open access: bronze, 2014
Elham Shabani   +9 more
openalex   +1 more source

Protein engineering strategies to optimise recombinant product synthesis and accumulation in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
Summary In plant molecular farming, recombinant products include traditional protein targets, such as antibodies, antigens, and enzymes, but also increasingly refers to high‐value peptides, and small molecules produced by heterologous enzymatic pathways.
Maxim D. Harding, Frank Sainsbury
wiley   +1 more source

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