When, which and how to switch: Navigating JAK inhibitors in myelofibrosis
British Journal of Haematology, EarlyView.Navigating choice of JAK inhibitor (JAKi) therapy for patients with myelofibrosis who are JAKi‐naïve and for those who have previously been treated with a JAKi.
Jennifer O'Sullivan +2 more
wiley +1 more source
Neuroprotective effect of erythropoietin on anesthesia-induced neurotoxicity through the modulation of autophagy in [PDF]
Korean Journal of AnesthesiologyBackground The anti-oxidative, anti-inflammatory, and anti-apoptotic effects of erythropoietin may provide neuroprotective effects. Erythropoietin also modulates autophagy signaling that may play a role in anesthesia-induced neurotoxicity (AIN).
Bon-Wook Koo +5 more
doaj +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Aims Sotagliflozin, an inhibitor of sodium‐glucose co‐transporter (SGLT)‐1 and 2, reduces albuminuria, slows GFR decline, and may have diuretic and osmoregulatory effects. The effect of sotagliflozin added to insulin was assessed on markers of neurohormone activation and volume homeostasis in patients with type 1 diabetes (T1D).
Massimo Nardone +6 more
wiley +1 more source
Биопрепараты: Профилактика, диагностика, лечение, 2018 The method for the assessment of biological activity of erythropoietin preparations in vitro on TF-1 sensitive cells culture has been developed. The special characteristics of measurements and calculations of the biological activity of erythropoietin ...
N. A. Gavrilova +3 more
doaj
Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice [PDF]
, 2018 Richard Coffey +5 more
openalex +1 more source
ERYTHROPOIETIN, MYOINOSITOL AND METFORMIN MODULATE INSULIN SENSITIVITY INDICES, PANCREATIC BETA CELL MASS AND HEPATOCELLULAR CHANGES IN A RAT MODEL OF POLYCYSTIC OVARY SYNDROME [PDF]
, 2022 Sherine Ahmed Mohammed +4 more
openalex +1 more source
Whole Blood Transcriptomic Analysis of Sickle Cell Trait
European Journal of Haematology, EarlyView.ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson +12 more
wiley +1 more source
Serum Erythropoietin level in children with different degrees of chronic renal failure
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2000 Objective: Kidneys are major sites of erythropoietin production and in chronic renal failure (CRF), erythropoietin production decreases and leads to anemia. This study was done in children with different degrees of CRF and with primary disease of tubules
Gh Al-Hosseini Hashemi +2 more
doaj
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
The FEBS Journal, EarlyView.Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source