Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells. [PDF]
PLoS Neglected Tropical Diseases, 2009 Infection of the mammalian host by the parasitic helminth Schistosoma mansoni is accompanied by the release of excretory/secretory molecules (ES) from cercariae which aid penetration of the skin.
Ross A Paveley +4 more
doaj +3 more sources
Mast Cell Subsets and Their Functional Modulation by the Acanthocheilonema viteae Product ES-62 [PDF]
Journal of Parasitology Research, 2013 ES-62, an immunomodulator secreted by filarial nematodes, exhibits therapeutic potential in mouse models of allergic inflammation, at least in part by inducing the desensitisation of FcεRI-mediated mast cell responses.
Dimity H. Ball +7 more
doaj +5 more sources
The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype [PDF]
, 2013 We previously demonstrated inhibition of ovalbumin (OVA)-induced allergic airway hyper-responsiveness in the mouse using ES-62, a phosphorylcholine-containing glycoprotein secreted by the filarial nematode, Acanthocheilonema viteae.
Harnett, M.M. +30 more
core +4 more sources
Localisation of the Ki-67 antigen within the nucleolus: Evidence for a fibrillarin-deficient region of the dense fibrillar component [PDF]
, 1996 The Ki-67 antigen is detected in proliferating cells in all phases of the cell division cycle. Throughout most of interphase, the Ki-67 antigen is localised within the nucleolus.
Kill, IR
core +6 more sources
NanoAPC deliver antigen, IL-2 and co-stimulatory molecules to antigen specific T cells and activate viral specific T cells in chronic infections [PDF]
, 2011 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The study of the immune system has provided insight in the mechanism of protection induced by vaccination; primarily that most clinically protective ...
Liu, Mengya
core +7 more sources
COMPARATIVE STUDY FOR DIAGNOSIS OF FASCIOLIASIS IN CATTLE AND BUFFALOES BY ANTIBODY AND ANTIGEN DETECTION [PDF]
Assiut Veterinary Medical Journal, 2005 As a disease of domestic ruminants, fascioliasis is of considerable economic importance. The current research adopted two main methods for diagnosis of fascioliasis in naturally infected cattle and buffaloes.
EMAN H. ABDEL-RAHMAN, A.A. GHAZY
doaj +1 more source
Pathogens, 2021 Ascaris suum, the most important pig parasite, also infects humans as a zoonotic pathogen. Malabsorption upon infection probably results from impaired nutrient transport, presumably mediated by the parasite’s excretory-secretory (ES) or cuticle somatic ...
Sarina Koehler +6 more
doaj +1 more source
DIAGNOSTIC VALUE OF SOME PARASCARIS EQUORUM ANTIGENS IN FOALS [PDF]
Assiut Veterinary Medical Journal, 2008 Three Parascaris equorum antigens were evaluated in diagnosis of current infection with P. equorum in foals’ sera using enzyme linked immunosorbant assay (ELISA) technique. The excretory-secretory antigen (ES) showed marked potency than the crude and egg
H.A. SHALABY +2 more
doaj +1 more source
Role of immunotherapy in Ewing sarcoma
Journal for ImmunoTherapy of Cancer, 2020 Ewing sarcoma (ES) is thought to arise from mesenchymal stem cells and is the second most common bone sarcoma in pediatric patients and young adults. Given the dismal overall outcomes and very intensive therapies used, there is an urgent need to explore ...
Erin Morales +5 more
doaj +1 more source
PLOS ONE, 2017 The digenetic trematode Fasciola gigantica is a parasite of great agricultural and economic importance. Along with Fasciola hepatica, F. gigantica incurs huge economic losses to the agricultural sector. Because of unavailability of an effective and commercial vaccine, the earliest diagnosis of the disease is the only way to control the disease.
M. A. Hannan Khan +5 more
openaire +4 more sources