The Carcinoembryonic Antigen Gene Family [PDF]
The molecular cloning of carcinoembryonic antigen (CEA) and several cross-reacting antigens reveals a basic domain structure for the whole family, which shows structural similarities to the immunoglobulin superfamily.
Zimmermann, Wolfgang, Thompson, John A.
core +1 more source
Background: Linguatula serrata is a causative agent of visceral and nasopharyngeal linguatulosis in humans and animals. The aim of the present study was to investigate the immune response of dogs experimentally infected by L.
Alireza Alborzi +4 more
doaj +1 more source
Characterization of Spirometra erinaceieuropaei Plerocercoid Cysteine Protease and Potential Application for Serodiagnosis of Sparganosis. [PDF]
BACKGROUND:Sparganosis is a neglected but important food-borne parasitic zoonosis. Clinical diagnosis of sparganosis is difficult because there are no specific manifestations.
Li Na Liu +7 more
doaj +1 more source
Low antigenicity of hematopoietic progenitor cells derived from human ES cells
Eun-Mi Kim1, Nicholas Zavazava1,21Department of Internal Medicine, University of Iowa and Veterans Affairs Medical Center, Iowa City, Iowa, USA; 2Immunology Graduate Program, University of Iowa, Iowa City, Iowa, USAAbstract: Human embryonic stem (hES) cells are essential for improved understanding of diseases and our ability to probe new therapies for ...
Eun-Mi Kim,, Zavazava,Nicholas
openaire +4 more sources
Therapeutic approaches for treating hemophilia A using embryonic stem cells
Hemophilia A is an X-linked rescessive bleeding disorder that results from F8 gene aberrations. Previously, we established embryonic stem (ES) cells (tet-226aa/N6-Ainv18) that secrete human factor VIII (hFVIII) by introducing the human F8 gene in mouse ...
Shogo Kasuda +4 more
doaj +1 more source
Declining HIV-1 Prevalence and Incidence among Police Officers - A potential Cohort for HIV Vaccine Trials, in Dar es Salaam, Tanzania. [PDF]
A safe effective and affordable HIV vaccine is the most cost effective way to prevent HIV infection worldwide. Current studies of HIV prevalence and incidence are needed to determine potentially suitable cohorts for vaccine studies.
Munseri, P. J. +27 more
core +2 more sources
Background The excretory–secretory (ES) antigens of Trichinella spiralis muscle larvae (ML) are the most commonly used diagnostic antigens for trichinellosis.
Ge-Ge Sun +8 more
doaj +1 more source
Evaluation of Enzyme- linked Immunosorbaent Assay, Using Somatic and Excretory-Secretory Antigens of Strongyloides stercoralis for the Serodiagnosis of Strongyloidosis [PDF]
Strongyloidiasis, caused by a nematode parasite so-called Strongyloides stercoralis is one of the major human intestinal nematode infections. Considering that stool examination for Strongyloides larvae is not a sensitive method and immunodiagnostic ...
Rokni MB, Kia EB
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

