Results 91 to 100 of about 4,578 (289)

Different Pattern of Treatment Failure After Chemoradiation Between p16+ and p16− Patients Affected by Oropharyngeal Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Oropharyngeal cancer (OPC) exhibits distinct clinical behaviors according to HPV/p16 status and smoking exposure. While HPV‐positive OPC generally shows superior survival, differences in recurrence patterns remain unclear. Methods A retrospective multicenter analysis of 674 AJCC VII edition Stage III–IVa/b OPC patients treated with ...
Riccardo Gili, Paolo Bossi, Luca Lalli, Lisa Francesca Linda Licitra, Marta Maddalo, Almalina Bacigalupo, Liliana Belgioia, Jon Cacicedo, Nadia Facchinetti, Almudena Garcia Castano, Marc Oliva, Pierluigi Bonomo, Giuseppe Sanguineti, Pierfrancesco Franco, Athanassios Argiris, Amanda Psyrri, Ester Orlandi   +16 more
wiley   +1 more source

MUC1 as a Survival Effector of Radiotherapy‐Induced Epithelial Hybrid States in Basal‐Like Breast Cancer

International Journal of Cancer, EarlyView.
Basal‐like breast cancer (BLBC) is aggressive and often exhibits inherent or acquired resistance to radiotherapy (RT), a primary treatment option. RT resistance is underpinned by molecular alterations, many of which are poorly understood. Here, RT‐induced transcriptomic changes were analyzed using bulk and spatial sequencing in a BLBC mouse model and ...
Garyfallia Pantelaiou‐Prokaki, Husam Bamahmoud, Nadine S. Georges, Shaishavi Jansari, Annika Jung, Daniela Grimm, Evangelos Prokakis, Fabian Alexander Gayer, Maryam Deldar, Christian Dullin, Julia Gallwas, Florian Wegwitz, Frauke Alves   +12 more
wiley   +1 more source

Le crayon et le clavier pour écrire au préscolaire et en première anneée [PDF]

, 2014
Plusieurs études se sont intéressées à l’utilisation de l’ordinateur comme outil pédagogique pour améliorer la compétence à écrire des élèves de même qu’aux productions écrites et aux préoccupations des élèves lorsqu’ils écrivent avec le crayon ...
Boudreau, Monica, Lavoie, Natalie
core  

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

Conhecimento sobre o molusco gigante africano Achatina fulica entre estudantes de uma escola pública na Região Metropolitana do Recife.

Biotemas, 2007
Achatina fulica Bowdich, 1822, espécie de molusco tropical africano, foi introduzida no Brasil em 1988 para substituir o caramujo europeu Helix sp. – o escargot.
Renata Manzi de Souza, Ângelo Giuseppe Chaves Alves, Marcos Souto Alves   +2 more
doaj  

Microemulsion‐Based Drilling Fluids Incorporating Seashell Residue Powder: A Sustainable Approach to Fluid Loss Control

Journal of Surfactants and Detergents, EarlyView.
Two microemulsion‐based drilling fluids incorporating SSRP were formulated using pine oil, the nonionic surfactant Alkonat L100W, and a glycerol/water solution. The results provide valuable insights into how surfactant‐assisted microemulsion systems can be engineered to enhance the performance and eco‐efficiency of drilling fluids.
Luara Ribeiro Viana, Raphael Ribeiro da Silva, João Pedro Gonçalves de Souza Soares, José Cavalcante de Queiroz Neto, Maria Eduarda Araújo Pessoa, Rafael Peixoto Alves, Fabiola Dias da Silva Curbelo   +6 more
wiley   +1 more source

« Friches et Aliens » : un module de l'expédition Santo 2006 [PDF]

, 2008
International audienceL’expédition Santo 2006 s’est fixée pour objectif de réaliser l’inventaire le plus exhaustif possible de la biodiversité, tant marine que terrestre et dulçaquicole, de l’île océanique tropicale d’Espiritu Santo (Vanuatu, ex-Nouvelles-
Lorvelec, Olivier, Pascal, Michel, Soldati, Laurent   +2 more
core   +1 more source

CardiacDP: An R package for rapid automated cardiac data processing, integrating autocorrelation, a genetic algorithm, and a tracking index

Limnology and Oceanography: Methods, EarlyView.
Abstract Heart rate is a popular proxy of physiological responses, but the highly complex and variable cardiac data obtained from organisms such as marine invertebrates pose a major challenge to efficient and accurate data processing. To address this, we developed a novel, integrative algorithm for rapid and automated cardiac data processing.
Sarah L. Y. Lau, Adrian T. C. Wong, Yi‐Fei Gu, Tin Yan Hui   +3 more
wiley   +1 more source

Bio‐Based Microfluidics With Snail Slime: A By‐Product of Agriculture Plays an Exciting Role in the Chemistry of Microfluidic Reaction Chambers

Macromolecular Rapid Communications, EarlyView.
Due to a broad spectrum of active ingredients, snail slime presents a variety of exciting physical properties and chemical reactivities. Especially in the role of the reduction‐ and stabilizing agent for the manufacturing of gold nanoparticles, its great potential is revealed. Utilising the proteins found in slime, Nanoparticle‐comprising hydrogels are
Andrea Koball, Jens Gaitzsch
wiley   +1 more source