Results 151 to 160 of about 4,520 (272)

MicroRNA profiling identifies novel regulators of stem cell function in the adult Drosophila intestine. [PDF]

Sci Rep
Sreejith P, Yon J, Lapenta K, Biteau B.
europepmc   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

Environmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa, Analía Ale, Azael Francisco Silva Neto, Lorena De Mendonça Lucena, Marcelo Estrella Josende, Milena Ferreira de Lima, Rhayanny Kethylly Pereira Santos, Martín Federico Desimone, Priscila Gubert, José María Monserrat   +9 more
wiley   +1 more source

Artificial intelligence agents in healthcare research: A scoping review. [PDF]

PLoS One
Njei B, Al-Ajlouni YA, Sidney Kanmounye U, Boateng S, Loic Nguefang G, Njei N, Hamouri S, Al-Ajlouni AF.   +7 more
europepmc   +1 more source

Enhancement of immune checkpoint inhibitor efficacy by DHX58+ SELL+ T cells in advanced gastric cancer

VIEW, EarlyView.
We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen, Youdong Liu, Hongda Pan, Tianyi Cai, Mingde Zang, Xiaowen Liu, Ziwen Long, Xin Fan, Jun Lu, Fenglin Liu   +9 more
wiley   +1 more source

Inhibition of PHF1 promotes ferroptosis via IRES‐dependent Snail translation regulation in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie, Shan Jin, Yao Zhan, Tiantian Du, Yaqi Dong, Peilong Li, Xiaoshi Zhang, Qiuchen Qi, Jie Gao, Chuanxin Wang   +9 more
wiley   +1 more source

Local food production and local identity [PDF]

, 2015
Csurgó, Bernadett, Megyesi, Gergely Boldizsár   +1 more
core   +1 more source

Escargot on the go [PDF]

Nature, 2013
openaire   +1 more source

Delisting the Northern Rocky Mountain gray wolf from the US Endangered Species Act: an assessment of political discourse over 20 years

Wildlife Biology, EarlyView.
Feared, revered, and politicized, wolves have long captured human imagination, and ignited fierce conservation conflicts. In the United States, the Endangered Species Act protects species at risk of extinction from human impacts. This far‐reaching legislation, which impacts development and state‐level wildlife management, has been fraught with legal ...
Iree Wheeler, Paisley Blair, Noah Creany, Hannah Manire, Daniel Morris, Sofia Mollett, Steelle S. Scearce, Temple Stoellinger, Janna R. Willoughby, Kelly H. Dunning   +9 more
wiley   +1 more source

A single-cell transcriptomic dataset of enterocyte-specific HHEX knockdown in the Drosophila larval midgut. [PDF]

Sci Data
Tu Z, Hu Q, Jia Z, Wang Y, Yu T, Liu L, Xu X, Hu Y, Wang M.   +8 more
europepmc   +1 more source

Drosophila larval epidermal cells only exhibit epidermal aging when they persist to the adult stage.

J Exp Biol, 2021
Wang Y, Burra S, Galko MJ.
europepmc   +1 more source