Results 191 to 200 of about 4,520 (272)

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

British Journal of Pharmacology, EarlyView.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim, Junhyuk Woo, Sungmin Pak, Joonho Paik, Gyu‐Sang Hong, Ji Hun Wi, Sanghee Lee, Cristina Fenollar‐Ferrer, Kyungreem Han, Young Kee Shin, Uhtaek Oh   +10 more
wiley   +1 more source

Drosophila melanogaster models for investigating inflammatory bowel disease: Methods, pathology, mechanisms, and therapeutic approaches. [PDF]

Biomol Biomed
Li X, Sun S, Liu X, Meng Q, Tian M, Li J, Ren S, Huang Z, Wang Y, Du S.   +9 more
europepmc   +1 more source

The Rouen Post, October 1936 [PDF]

, 1936

core   +1 more source

Single‐Cell Analysis Identified a Recurrent Malignant‐Associated Transcriptional State in Colorectal Cancer

Cancer Science, EarlyView.
Colorectal cancer (CRC) shows high molecular heterogeneity, yet single‐cell data from Japanese patients are limited. We performed scRNA‐seq on tumors and adjacent normal tissues from four Japanese CRC patients and identified a shared malignant cell cluster with high KCNQ1OT1 expression and reduced RASSF6 levels.
Sadahiro Iwabuchi, Kentaro Sawada, Motohiro Kojima, Miho Ozawa, Hiroya Taniguchi, Hideaki Bando, Kazumi Abe, Yuta Kuze, Kiyomi Imamura, Yukie Kashima, Yoshihiko Hirohashi, Atsushi Tajima, Toshihiko Torigoe, Yutaka Suzuki, Takayuki Yoshino, Shinichi Hashimoto   +15 more
wiley   +1 more source

From plant to fabric: Environmental opportunities associated with annatto dye for sustainable development in the textile industry

Coloration Technology, EarlyView.
Abstract Natural dyes are compounds that occur naturally in several organisms and are classified based on chemical structure and application method. The literature cites several natural dyes used in industrial transformation processes. Annatto dye is used in the food industry, and its biological pigment is extracted from the annatto seed. However, this
Marcel Jefferson Gonçalves, Tania Maria Costa, Karine Thaise Rainert, Vera Lúcia Vogel Faustino dos Santos, Ivonete Oliveira Barcellos, Lorena Benathar Ballod Tavares   +5 more
wiley   +1 more source

Compte rendu de mission au Guyana, du 22 au 26 avril 2008 [PDF]

, 2008
Teycheney, Pierre-Yves
core  

Cellular Signalling Networks in High Altitude Pulmonary Hypertension: From Canonical Pathways to Emerging Targets

Cell Proliferation, EarlyView.
This review elucidates the intricate cellular signalling networks involved in high‐altitude pulmonary hypertension (HAPH), integrating canonical pathways like HIF, MAPK and BMP with emerging targets such as Wnt/β‐catenin, Notch, Hippo‐YAP and IL‐6. It highlights potential therapeutic strategies targeting these pathways to mitigate vascular remodelling ...
Sheng Ding, Ju Chen, Zhaoyang Li, Yang Yu, Weijie Wang, Yan Liao, Jin Yang, Dianxiang Lu, Yujiang Fan   +8 more
wiley   +1 more source

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

Cell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang, Ling Rao, Xiaofang Li, Miaofen Zhang, Huiting Huang, Zhiyan Luo, Gang Liao, Yong Jiang, Shaofeng Zhan, Qiong Liu, Xiufang Huang   +10 more
wiley   +1 more source

1164. Echinacea simulata McGregor

Curtis's Botanical Magazine, EarlyView.
Summary Echinacea simulata McGregor (Compositae: Heliantheae: Zinniinae) is described and illustrated. Notes are provided for the species' cultivation, propagation, likely pests and diseases, and availability. A full synonymy is given, along with type citations and known presence of type material, together with relevant notes. Statements of the species'
Nicholas Hind, Deborah Lambkin
wiley   +1 more source

1165. Echinacea purpurea (L.) Moench

Curtis's Botanical Magazine, EarlyView.
Summary Echinacea purpurea (L.) Moench (Compositae: Heliantheae: Zinniinae) is described and illustrated with a colour plate and black and white text figure. An introduction to the history of the appearance of this species in the Magazine appears in brief, together with comments on the treatment of the genus, and the available generic revisions.
Nicholas Hind, Masumi Yamanaka, Naoko Yasue   +2 more
wiley   +1 more source